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Table 2 Partial correlations of cystatin C and creatinine-based eGFR with inflammatory and procoagulant markers at the baseline visit of the MESA study, stratified by presence of chronic kidney disease

From: Association of kidney function with inflammatory and procoagulant markers in a diverse cohort: A cross-sectional analysis from the Multi-Ethnic Study of Atherosclerosis (MESA)

Marker of Kidney Function

Inflammatory Marker

 

CRP

(N = 6750)

IL-6

(N = 6622)

TNF-αR1

(N = 995)

ICAM-1

(N = 2611)

Fibrinogen

(N = 6750)

Factor VIII

(N = 6750)

Cystatin C

0.075*

0.156*

0.748*

0.209*

0.137*

0.112*

Creatinine-based eGFR

-0.019

-0.003

-0.285*

0.025

-0.059*

-0.034*

Persons with CKD

      

   Cystatin C

0.116*

0.230*

0.903*

0.160*

0.248*

0.140*

   Creatinine-based eGFR

-0.101*

-0.139*

-0.763*

-0.035

-0.286*

-0.146*

Persons without CKD

      

   Cystatin C

0.085*

0.180*

0.557*†

0.261*

0.111*†

0.085*

   Creatinine-based eGFR

-0.004‡

0.025‡

-0.168*‡

0.027

-0.021‡

0.017‡

  1. Partial correlations adjusted for age, gender, race/ethnicity, and BMI
  2. Chronic kidney disease (CKD) defined as eGFR < 60 mL/min/1.73 m2
  3. * Correlation is significant at the 0.01 level (2-tailed).
  4. † Correlation between cystatin C and the biomarker is significantly stronger among participants with CKD
  5. ‡ Correlation between creatinine-based eGFR and the biomarker is significantly stronger among participants with CKD
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BMC Nephrology

ISSN: 1471-2369

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