Table 1 Clinical and demographic characteristics of the cohort comparing no-AKI vs transient AKI vs intrinsic AKI
no AKI (n = 28) | Transient AKI (n = 57) | Intrinsic AKI (n = 22) | p value | |
|---|---|---|---|---|
Gender male (%) | 51.7 | 54.4 | 59.1 | 0.93 |
Age (years,mean/sd) | 55.4(17.3) | 62.6(13.2) | 63.1(14.9) | 0.08 |
Reason for admission (%): | 0.11 | |||
Respiratory | 46.4 | 38.6 | 36.4 | |
Abdominal | 21.4 | 33.3 | 36.4 | |
Urinary | 7.1 | 8.8 | 0 | |
Endocarditis | 3.6 | 7.0 | 0 | |
Neurological | 7.1 | 0 | 4.5 | |
Catheter | 10.7 | 1.8 | 0 | |
Other | 3.6 | 10.5 | 22.7 | |
CKD on admission (eGFR according to MDRD <60 mL/min/1,73 m2) (%) | 10.7 | 8.8 | 9.1 | 1 |
APACHE II score on the first day of admission | 21(10) | 22(8) | 24.5(9) | 0.08 |
Fluid balance first 24 hours (liter, mean/sd) | 2.2(1.8) | 3.1(1.9) | 5.4(2.7) | <0.001 |
Use of diuretics on the first day of admission (%) | 7.1 | 14 | 22.7 | 0.29 |
RRT need during ICU stay (%) | 0 | 1.8 | 59.1 | <0.001 |
Vasopressor use (%) | 32.1 | 61.4 | 86.4 | <0.001 |
Total dose of noradrenaline first 24 h in μg/kg/min (mean/sd) | 0.05(0.11) | 0.09(0.12) | 0.20(0.22) | 0.001 |
Maximum dose of noradrenaline during first 24 h in μg/kg/min (mean/sd) | 0.12(0.23) | 0.25(0.31) | 0.54(0.55) | 0.008 |
Need for ventilation during ICU stay (%) | 39.3 | 50.9 | 86.4 | 0.002 |
LOS in the ICU (days) | 5(6) | 5(10) | 38(32) | 0.014 |
ICU mortality (%) | 21.4 | 15.8 | 54.2 | 0.002 |
Mortality at 90 days (%) | 28.6 | 24.6 | 59.1 | 0.012 |