Feeding soy protein isolate and oils rich in omega-3 polyunsaturated fatty acids affected mineral balance, but not bone in a rat model of autosomal recessive polycystic kidney disease

Table 5 Trabecular bone microarchitecture in growing female PCK rats fed different diets

Measurement*	Casein + CO	Casein + SO	SPI + SO	SPI + SB	P -value
Femur
BV/TV (%)	14.30 ± 0.54	14.00 ± 0.58	12.95 ± 0.96	13.64 ± 0.86	0.61
TbN (per mm)	2.87 ± 0.11	2.74 ± 0.11	2.77 ± 0.20	2.86 ± 0.10	0.87
TbTh (mm)	0.07 ± 0.0009	0.07 ± 0.001	0.06 ± 0.001	0.07 ± 0.002	0.18
TbSp (mm)	0.36 ± 0.01	0.38 ± 0.01	0.40 ± 0.04	0.36 ± 0.01	0.65
Conn (1/mm³)	80.77 ± 2.99	76.47 ± 2.83	77.06 ± 5.26	77.83 ± 3.59	0.86
SMI	2.28 ± 0.03	2.30 ± 0.05	2.12 ± 0.06	2.36 ± 0.07	0.31
Tibia
BV/TV (%)	9.43 ± 0.62	9.67 ± 0.63	9.13 ± 0.84	9.24 ± 0.83	0.96
TbN (per mm)	2.51 ± 0.13	2.44 ± 0.17	2.39 ± 0.19	2.61 ± 0.16	0.82
TbTh (mm)	0.06 ± 0.001	0.06 ± 0.0009	0.06 ± 0.001	0.06 ± 0.001	0.33
TbSp (mm)	0.42 ± 0.02	0.44 ± 0.30	0.46 ± 0.05	0.41 ± 0.03	0.63
Conn (1/mm³)	43.00 ± 4.56	43.58 ± 4.59	43.53 ± 6.11	43.26 ± 6.34	1.00
SMI	2.85 ± 0.05	2.80 ± 0.04	2.88 ± 0.07	2.88 ± 0.07	0.72

*Values are expressed as the mean ± SEM of n = 12 bones/group. Abbreviations are CO corn oil, SO soybean oil, SPI soy protein isolate, SB 1:1 soybean oil:salmon oil blend, BV/TV trabecular bone volume per unit of total volume, TbN trabecular number, TbTh trabecular thickness, TbSp trabecular space, Conn connectivity, SMI structure model index.

ISSN: 1471-2369