Feeding soy protein isolate and oils rich in omega-3 polyunsaturated fatty acids affected mineral balance, but not bone in a rat model of autosomal recessive polycystic kidney disease

Table 6 Cortical bone microarchitecture in growing female PCK rats fed different diets

Measurement*	Casein + CO	Casein + SO	SPI + SO	SPI + SB	P value
Femur
Cortical Thickness (mm)	0.55 ± 0.008	0.55 ± 0.004	0.56 ± 0.004	0.55 ± 0.004	0.47
Cortical Area (mm²)	4.49 ± 0.03	4.40 ± 0.05	4.56 ± 0.03	4.52 ± 0.05	0.06
Medullary Area (mm²)	0.26 ± 0.006	0.25 ± 0.007	0.25 ± 0.006	0.26 ± 0.007	0.94
Porosity (%)	5.42 ± 0.12	5.45 ± 0.15	5.28 ± 0.14	5.39 ± 0.12	0.78
Tibia
Cortical Thickness (mm)	0.52 ± 0.004	0.53 ± 0.003	0.53 ± 0.01	0.53 ± 0.006	0.59
Cortical Area (mm²)	2.90 ± 0.03	2.94 ± 0.03	2.88 ± 0.05	2.98 ± 0.04	0.29
Medullary Area (mm²)	0.20 ± 0.004	0.19 ± 0.003	0.18 ± 0.004	0.19 ± 0.005	0.46
Porosity (%)	6.32 ± 0.02	6.06 ± 0.09	6.11 ± 0.13	6.04 ± 0.16	0.37

*Values are expressed as the mean ± SEM of n = 12 bones/group. Abbreviations are CO corn oil, SO soybean oil, SPI soy protein isolate, SB 1:1 soybean oil:salmon oil.

ISSN: 1471-2369