Feeding soy protein isolate and oils rich in omega-3 polyunsaturated fatty acids affected mineral balance, but not bone in a rat model of autosomal recessive polycystic kidney disease

Table 7 Bone strength measurements in growing female PCK rats fed different diets

Measurement*	Casein + CO	Casein + SO	SPI + SO	SPI + SB	P value
Femur
Peak Force (N)	37.2 ± 2.6	42.5 ± 2.7	40.4 ± 2.6	44.5 ± 3.0	0.26
Ultimate Stiffness (N/S)	437.6 ± 23.3	437.7 ± 37.1	385.6 ± 33.7	429.4 ± 29.8	0.63
Ultimate Bending Stress (N/mm²)	41.8 ± 3.2	47.3 ± 2.3	45.7 ± 3.0	48.6 ± 3.5	0.40
Young’s Modulus (N/mm²)	1160.6 ± 54.0	1171.5 ± 106.2	1040.0 ± 100.6	1117.8 ± 99.2	0.75
Tibia
Peak Force (N)	19.2 ± 1.3	22.3 ± 1.7	20.0 ± 1.7	20.7 ± 1.3	0.57
Ultimate Stiffness (N/S)	178.0 ± 13.1	171.3 ± 13.0	158.9 ± 7.9	161.2 ± 10.9	0.61
Ultimate Bending Stress (N/mm²)	51.5 ± 3.4	61.7 ± 4.0	56.37 ± 5.58	57.41 ± 5.26	0.5
Young’s Modulus (N/mm²)	1938.8 ± 166.7	1970.0 ± 172.8	1815.6 ± 125.1	1765.5 ± 150.5	0.76

*Values are expressed as the mean ± SEM of n = 12 bone pairs/group. Abbreviations are CO corn oil, SO soybean oil, SPI soy prtein isolate, SB 1:1 soybean oil:salmon oil blend.

ISSN: 1471-2369