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Table 3 Adjusted odds ratios (ORs) with associated 95% confidence interval (CI) for reduced renal function, albuminuira and CKD

From: Association of serum irisin and body composition with chronic kidney disease in obese Chinese adults: a cross-sectional study

  Reduced renal function Albuminuira CKD
Variables OR 95% CI P value OR 95% CI P value OR 95% CI P value
Model 1          
BMI (kg/m2) 1.073 0.971-1.186 0.2 1.09 1.047-1.148 <0.001* 1.098 1.050-1.149 <0.001*
Waist circumference (cm) 0.995 0.947-1.045 0.8 1.039 1.018-1.061 <0.001* 1.031 1.011-1.052 0.003*
Body fat mass (kg) 1.084 1.023-1.150 0.007* 1.049 1.018-1.080 0.002* 1.055 1.026-1.086 <0.001*
Body fat rate (%) 1.083 1.004-1.167 0.038* 1.082 1.043-1.121 <0.001* 1.085 1.048-1.124 <0.001*
Serum irisin† 0.987 0.721-1.353 0.9 0.948 0.820-1.096 0.5 0.949 0.826-1.091 0.5
Serum irisin          
(Quartile 2 vs. Quartile 1) 1.616 0.669-3.906 0.3 0.926 0.605-1.416 0.7 1.007 0.671-1.511 1.0
(Quartile 3 vs. Quartile 1) 1.228 0.493-3.057 0.7 1.287 0.859-1.926 0.2 1.340 0.908-1.979 0.1
(Quartile 4 vs. Quartile 1) 0.766 0.278-2.110 0.6 0.740 0.479-1.141 0.2 0.721 0.474-1.096 0.1
Model 2          
BMI (kg/m2) 1.074 0.958-1.205 0.2 1.100 1.046-1.156 <0.001* 1.102 1.049-1.158 <0.001*
Waist circumference (cm) 1.011 0.959-1.066 0.7 1.038 1.015-1.061 0.001* 1.034 1.011-1.057 0.003*
Body fat mass (kg) 1.093 1.020-1.172 0.012* 1.053 1.019-1.087 0.002* 1.059 1.026-1.093 <0.001*
Body fat rate (%) 1.088 1.000-1.183 0.1 1.083 1.042-1.125 <0.001* 1.087 1.047-1.129 <0.001*
Serum irisin † 0.992 0.697-1.412 1.0 0.914 0.784-1.066 0.3 0.917 0.859-1.379 0.3
Serum irisin          
(Quartile 2 vs. Quartile 1) 1.738 0.640-4.722 0.3 0.760 0.477-1.209 0.2 0.848 0.542-1.326 0.5
(Quartile 3 vs. Quartile 1) 1.334 0.471-3.780 0.6 1.106 0.711-1.719 0.7 1.191 0.775-1.831 0.4
(Quartile 4 vs. Quartile 1) 0.607 0.183-2.008 0.4 0.641 0.401-1.024 0.1 0.620 .392-0.980 0.041*
Model 3          
BMI (kg/m2) 1.031 0.910-1.167 0.6 1.053 0.996-1.113 0.1 1.052 0.996-1.110 0.1
Waist circumference (cm) 0.997 0.945-1.053 0.9 1.023 0.998-1.048 0.1 1.017 0.993-1.041 0.2
Body fat mass (kg) 1.076 0.999-1.159 0.1 1.034 0.998-1.071 0.1 1.039 1.004-1.076 0.029*
Body fat rate (%) 1.062 0.969-1.164 0.2 1.046 1.002-1.092 0.039* 1.049 1.006-1.093 0.025*
Serum irisin† 0.946 0.660-1.357 0.8 0.910 0.771-1.073 0.3 0.906 0.772-1.064 0.2
Serum irisin          
(Quartile 2 vs. Quartile 1) 1.609 0.579-4.472 0.4 0.786 0.485-1.272 0.3 0.873 0.549-1.388 0.6
(Quartile 3 vs. Quartile 1) 1.185 0.407-3.448 0.8 1.050 0.658-1.673 0.8 1.123 0.713-1.769 0.6
(Quartile 4 vs. Quartile 1) 0.507 0.147-1.746 0.3 0.611 0.373-1.000 0.050* 0.572 0.353-0.927 0.023*
  1. *p < 0.05.
  2. †OR and 95% CI was impressed as per SD increase of log transformed serum irisin.
  3. Abbreviations: BMI body mass index, CKD chornic kidney disease.
  4. Model 1 was adjusted for sex and age;
  5. Model 2 was further adjusted for educational level, ever smoking, ever drinking and physical activity.
  6. Model 3 was further adjusted for SBP, DBP, serum glubulin, hyperuricemia,TG,LDL, fasting glucose.