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Table 3 Adjusted odds ratios (ORs) with associated 95% confidence interval (CI) for reduced renal function, albuminuira and CKD

From: Association of serum irisin and body composition with chronic kidney disease in obese Chinese adults: a cross-sectional study

 

Reduced renal function

Albuminuira

CKD

Variables

OR

95% CI

P value

OR

95% CI

P value

OR

95% CI

P value

Model 1

         

BMI (kg/m2)

1.073

0.971-1.186

0.2

1.09

1.047-1.148

<0.001*

1.098

1.050-1.149

<0.001*

Waist circumference (cm)

0.995

0.947-1.045

0.8

1.039

1.018-1.061

<0.001*

1.031

1.011-1.052

0.003*

Body fat mass (kg)

1.084

1.023-1.150

0.007*

1.049

1.018-1.080

0.002*

1.055

1.026-1.086

<0.001*

Body fat rate (%)

1.083

1.004-1.167

0.038*

1.082

1.043-1.121

<0.001*

1.085

1.048-1.124

<0.001*

Serum irisin†

0.987

0.721-1.353

0.9

0.948

0.820-1.096

0.5

0.949

0.826-1.091

0.5

Serum irisin

         

(Quartile 2 vs. Quartile 1)

1.616

0.669-3.906

0.3

0.926

0.605-1.416

0.7

1.007

0.671-1.511

1.0

(Quartile 3 vs. Quartile 1)

1.228

0.493-3.057

0.7

1.287

0.859-1.926

0.2

1.340

0.908-1.979

0.1

(Quartile 4 vs. Quartile 1)

0.766

0.278-2.110

0.6

0.740

0.479-1.141

0.2

0.721

0.474-1.096

0.1

Model 2

         

BMI (kg/m2)

1.074

0.958-1.205

0.2

1.100

1.046-1.156

<0.001*

1.102

1.049-1.158

<0.001*

Waist circumference (cm)

1.011

0.959-1.066

0.7

1.038

1.015-1.061

0.001*

1.034

1.011-1.057

0.003*

Body fat mass (kg)

1.093

1.020-1.172

0.012*

1.053

1.019-1.087

0.002*

1.059

1.026-1.093

<0.001*

Body fat rate (%)

1.088

1.000-1.183

0.1

1.083

1.042-1.125

<0.001*

1.087

1.047-1.129

<0.001*

Serum irisin †

0.992

0.697-1.412

1.0

0.914

0.784-1.066

0.3

0.917

0.859-1.379

0.3

Serum irisin

         

(Quartile 2 vs. Quartile 1)

1.738

0.640-4.722

0.3

0.760

0.477-1.209

0.2

0.848

0.542-1.326

0.5

(Quartile 3 vs. Quartile 1)

1.334

0.471-3.780

0.6

1.106

0.711-1.719

0.7

1.191

0.775-1.831

0.4

(Quartile 4 vs. Quartile 1)

0.607

0.183-2.008

0.4

0.641

0.401-1.024

0.1

0.620

.392-0.980

0.041*

Model 3

         

BMI (kg/m2)

1.031

0.910-1.167

0.6

1.053

0.996-1.113

0.1

1.052

0.996-1.110

0.1

Waist circumference (cm)

0.997

0.945-1.053

0.9

1.023

0.998-1.048

0.1

1.017

0.993-1.041

0.2

Body fat mass (kg)

1.076

0.999-1.159

0.1

1.034

0.998-1.071

0.1

1.039

1.004-1.076

0.029*

Body fat rate (%)

1.062

0.969-1.164

0.2

1.046

1.002-1.092

0.039*

1.049

1.006-1.093

0.025*

Serum irisin†

0.946

0.660-1.357

0.8

0.910

0.771-1.073

0.3

0.906

0.772-1.064

0.2

Serum irisin

         

(Quartile 2 vs. Quartile 1)

1.609

0.579-4.472

0.4

0.786

0.485-1.272

0.3

0.873

0.549-1.388

0.6

(Quartile 3 vs. Quartile 1)

1.185

0.407-3.448

0.8

1.050

0.658-1.673

0.8

1.123

0.713-1.769

0.6

(Quartile 4 vs. Quartile 1)

0.507

0.147-1.746

0.3

0.611

0.373-1.000

0.050*

0.572

0.353-0.927

0.023*

  1. *p < 0.05.
  2. †OR and 95% CI was impressed as per SD increase of log transformed serum irisin.
  3. Abbreviations: BMI body mass index, CKD chornic kidney disease.
  4. Model 1 was adjusted for sex and age;
  5. Model 2 was further adjusted for educational level, ever smoking, ever drinking and physical activity.
  6. Model 3 was further adjusted for SBP, DBP, serum glubulin, hyperuricemia,TG,LDL, fasting glucose.