Figure 2

The changes in the levels of uTWEAK in patients with IgAN during follow-up. (A) Patients with clinical remission (n = 12): the levels of uTWEAK at the time of biopsy (median: 149.2, IQR 113.8–181.8 pg/mgCr) decreased significantly compared with those of therapy-induced clinical remission (median: 53.8, IQR 33.6–88.5 pg/mgCr; P = 0.003). (B) Patients with partial remission (n = 25): the levels of uTWEAK at the time of biopsy (median: 87.3, IQR 67.1–134.3 pg/mgCr) also decreased compared with those of therapy-induced partial remission (median: 58.4, IQR 42.6-81.3 pg/mgCr; P = 0.009). Wilcoxon signed-rank test.