TWEAK/Fn14 system and crescent formation in IgA nephropathy

BMC Nephrology

Table 3 Renal biopsy section evaluated with the Oxford classification (MEST)

Oxford classification		IgAN patients,	uTWEAK	P value ^a
Oxford classification		n (%)	(pg/mgCr, median, IQR)	P value ^a
M	0	59 (50.9)	92.1 (64.5, 136.7)	0.49
M	1	57 (49.1)	96.4 (66.6, 154.8)	0.49
E	0	77 (66.4)	87.3 (64.7, 141.1)	0.18
E	1	39 (33.6)	106.0 (67.8, 160.1)	0.18
S	0	62 (53.4)	81.2 (59.9, 145.5)	0.20
S	1	54 (46.6)	103.5 (73.3, 151.2)	0.20
T	0	106 (91.4)	91.1 (64.9, 145.5)	0.21
T	1, 2	10 (8.6)	150.9 (63.9, 184.7)	0.21

Abbreviations: uTWEAK, urinary TWEAK Mesangial hypercellularity score of ≤0.5 (M0) or >0.5 (M1), absence (E0) or presence (E1) of endocapillary hypercellularity, absence (S0) or presence (S1) of segmental glomerulosclerosis, and tubular atrophy/interstitial fibrosis of 0–25% (T0), 26–50% (T1), and >50% (T2).
^aMann-Whitney U test.

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