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Table 2 Unadjusted composite event and death rates by PTH change group at baseline with 1-year follow-up

From: Parathyroid hormone change after cinacalcet initiation and one-year clinical outcome risk: a retrospective cohort study

 

PTH response group

No PTH reduction

Quartile 1

Quartile 2

Quartile 3

Quartile 4

Composite event rates *

     

All patients

49.6

46.4

48.5

50.0

50.5

PTH 300-600 pg/mL

47.2

42.7

48.5

44.1

48.1

PTH > 600 pg/mL

52.6

49.3

48.4

55.5

52.6

Death rates

     

All patients

17.9

15.6

16.5

15.8

18.8

PTH 300-600 pg/mL

15.8

16.2

17.1

17.5

17.2

PTH > 600 pg/mL

20.5

15.1

16.1

14.3

20.0

  1. Patients were grouped based on quartiles of PTH decrease from first cinacalcet prescription. Patients whose PTH levels increased or remained unchanged were assigned to “no PTH reduction” group.
  2. Rates are expressed as events per 100 person-years.
  3. *Composite events include death, or hospitalization for stroke, congestive heart failure, or acute myocardial infarction.
  4. PTH, parathyroid hormone.