Table 1 Body weight, kidney weight, serum and urinary parameters in different groups after 8 weeks of treatment

Body weight (g)

240.3 ± 14.3

225.6 ± 11.5^△

226.4 ± 8.4

230.7 ± 12.0*

Kidney weight (g)

1.4 ± 0.1

1.6 ± 0.4^△

1.4 ± 0.1*

1.4 ± 0.2*

Kidney/body weight ratio (%)

5.7 ± 0.5

7.1 ± 1.0^△

6.3 ± 0.4*

6.2 ± 0.5*

SCr (μmol/L)

25.5 ± 10.8

51.0 ± 11.5^△

33.4 ± 8.7*

27.6 ± 6.9*

BUN (mmol/L)

15.4 ± 3.9

53.8 ± 11.8^△

26.1 ± 2.3*

25.4 ± 2.5*

Urinary albumin excretion (μg/day)

571.7 ± 72.4

1510.0 ± 392.7^△

799.4 ± 121.5*

757.9 ± 105.5*

Blood glucose (mmol/L)

8. 5 ± 0.9

21.9 ± 5.4^△

19.8 ± 1.2

12.3 ± 4.9*