Figure 2From: Effects of oxonic acid-induced hyperuricemia on mesenteric artery tone and cardiac load in experimental renal insufficiencyVasorelaxation in vitro. Line graphs show relaxation responses induced by acetylcholine in the absence (A) and presence (B) of L-NAME, and relaxations elicited by the NO donor nitroprusside (C), and the large conductance calcium-activated potassium channel opener NS-1619 (D) in the experimental groups; values are mean ± SEM, n = 10 for all groups; *P < 0.05, ANOVA for repeated measurements; †P < 0.05 NX groups compared with the Sham groups using two-way ANOVA for repeated measurements. Groups as in Figure 1.Back to article page