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Table 2 Outcomes at 90 and 180 days

From: Trace element supplementation in hemodialysis patients: a randomized controlled trial

 

Medium dose

Low dose

Medium and low dose combined

Standard dose

P-value

At day 90

     

Zinc

     

Low status, %

10 (21.7)

12 (26.1)

22 (23.9)

11 (23.9)

<0.99

Concentration, ug/L

1032 (960,1104)

970 (900,1039)

998 (945,1052)

932 (860,1003)

0.11

Selenium

     

Low status, %

8 (17.4)

10 (21.7)

18 (19.6)

15 (32.6)

0.09

Concentration, ug/L

146 (141,152)

140 (134,146)

143 (139,147)

131 (125,137)

<0.001

Inter-dialytic weight gain, kg

1.96 (1.70,2.22)

2.20 (1.94,2.46)

2.08 (1.88,2.28)

2.01 (1.74,2.28)

0.64

Salt sensitivity

     

Recognition improved

26 (55.3)

11 (24.4)

37 (40.2)

15 (32.6)

0.39

Sensitivity improved

11 (32.4)

7 (20.0)

18 (26.1)

8 (25.0)

0.91

At day 180

     

Zinc

     

Low status, %

10 (22.2)

14 (35.0)

24 (28.2)

8 (18.6)

0.24

Concentration, ug/L

1036 (964,1109)

927 (854,1001)

982 (928,1037)

972 (898,1046)

0.23

Selenium

     

Low status, %

9 (20.0)

11 (27.5)

20 (23.5)

15 (34.9)

0.17

Concentration, ug/L

139 (134,145)

135 (129,141)

137 (133,142)

135 (130,141)

0.07

Inter-dialytic weight gain, kg

1.99 (1.69,2.29)

2.16 (1.85,2.47)

2.17 (1.95,2.40)

1.97 (1.66,2.28)

0.26

Salt sensitivity

     

Recognition improved

22 (46.8)

16 (38.1)

38 (42.7)

15 (34.1)

0.24

Sensitivity improved

11 (31.4)

7 (20.6)

18 (26.1)

9 (28.1)

0.83

  1. Count (percentage) and adjusted mean (with 95% confidence intervals) where appropriate; values were adjusted for the NARP site and the mean baseline value. P-values statistically compare the combined dose group to the standard group. Bolded values are significantly different from the standard group. Low selenium status <121 ug/L. Low zinc status <815 ug/L.