Table 1 Profile of patients with ESRD overall over 10 years of the study
From: Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon
Variables | Overall | Male | Female | p-value | Quartiles of age | ||||
|---|---|---|---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | p-trend | |||||
N (%) | 863 (100) | 570 (66.0) | 293 (34.0) | 205 (23.8) | 218 (25.3) | 221 (25.6) | 219 (25.4) | ||
Marital status, n (%) | <0.001 | <0.001 | |||||||
Single | 169 (22.4) | 93 (18.7) | 76 (29.6) | 120 (67.4) | 31 (16.5) | 14 (7.0) | 4 (2.1) | ||
Married | 542 (71.9) | 393 (79.1) | 149 (58.0) | 55 (30.9) | 147 (27.1) | 169 (84.9) | 171 (90.5) | ||
Divorced | 3 (0.4) | 1 (0.2) | 2 (0.8) | 0 | 1 (0.5) | 1 (0.5) | 1 (0.5) | ||
Widow | 40 (5.3) | 10 (2.0) | 30 (11.7) | 3 (1.7) | 9 (4.8) | 15 (7.5) | 13 (6.9) | ||
Employment status, n (%) | <0.001 | <0.001 | |||||||
No employment | 250 (33.1) | 74 (15.8) | 176 (67.5) | 55 (30.2) | 1 (0.5) | 1 (0.5) | 1 (0.5) | ||
Private sector | 186 (24.6) | 147 (28.9) | 39 (14.9) | 48 (26.4) | 71 (37.2) | 44 (22.9) | 23 (12.1) | ||
Public sector | 198 (26.2) | 163 (33.0) | 35 (13.4) | 25 (13.7) | 71 (37.2) | 74 (38.5) | 28 (14.7) | ||
Retired | 121 (16.0) | 110 (22.3) | 11 (4.2) | 1 (0.5) | 1 (0.5) | 29 (15.1) | 90 (47.4) | ||
Mean age, yr. (SD) | 47.4 (14.8) | 48.8 (14.3) | 44.5 (15.5) | <0.001 | 26.3 (7.5) | 43.8 (3.5) | 53.3 (2.3) | 64.6 (6.1) | <0.001 |
Age, min-max, years | 7.0-87.0 | 11.0-87.0 | 7.0-79.0 | 7.0-37.0 | 38.0-49.3 | 50.0-57.0 | 58.0-87.0 | ||
Age, median [25th-75th percentiles] | 50 [38–58] | 51 [41–58] | 46 [32–56] | 44 [41–47] | 53 [51–55] | 63 [60–68] | |||
Any hypertension, n (%) | 763 (88.4) | 506 (88.8) | 257 (87.7) | 0.654 | 170 (82.9) | 180 (82.6) | 209 (94.6) | 204 (93.2) | <0.001 |
Any heart disease, n (%) | 146 (16.9) | 99 (17.4) | 47 (16.0) | 0.701 | 16 (7.8) | 42 (19.3) | 32 (14.5) | 56 (25.6) | <0.001 |
Diabetes, n (%) | 245 (28.4) | 177 (31.1) | 68 (23.2) | 0.017 | 9 (4.4) | 38 (17.4) | 102 (46.2) | 96 (43.8) | <0.001 |
HIV positive, n (%) | 69 (8.0) | 39 (6.8) | 30 (10.2) | 0.086 | 23 (11.2) | 24 (11.0) | 16 (7.2) | 6 (2.7) | <0.001 |
Alcohol drinker, n (%) | 142 (16.5) | 113 (19.8) | 29 (9.9) | <0.001 | 15 (7.3) | 39 (17.9) | 55 (24.9) | 33 (15.1) | 0.010 |
Smoking, n (%) | 65 (7.5) | 54 (9.5) | 11 (3.8) | 0.002 | 5 (2.4) | 19 (8.7) | 30 (13.6) | 11 (5.0) | 0.137 |
Cerebrovascular accidents, n (%) | 20 (2.3) | 16 (2.8) | 4 (1.4) | 0.235 | 1 (0.5) | 4 (1.8) | 9 (4.1) | 6 (2.7) | 0.053 |
Cancer, n (%) | 12 (1.4) | 5 (0.9) | 7 (2.4) | 0.120 | 2 (1.0) | 5 (2.3) | 3 (1.4) | 2 (0.9) | 0.731 |
Tuberculosis, n (%) | 14 (1.6) | 12 (2.1) | 2 (0.7) | 0.157 | 5 (2.4) | 4 (1.8) | 4 (1.8) | 1 (0.5) | 0.123 |
Mean Hb, g/dl (SD) | 7.7 (1.9) | 7.9 (2.0) | 7.4 (1.8) | 0.004 | 7.3 (1.8) | 7.7 (2.1) | 8.1 (1.9) | 7.8 (1.8) | 0.004 |
Mean Urea, mg/l (SD) | 2.4 (1.1) | 2.5 (1.2) | 2.2 (1.0) | 0.015 | 2.7 (1.1) | 2.6 (1.2) | 2.2 (1.0) | 2.2 (1.1) | <0.001 |
Mean creatinine,mg/l (SD) | 171.3 (88.5) | 175.8 (92.5) | 162.6 (79.9) | 0.064 | 198.0 (95.4) | 185.9 (91.7) | 160.9 (77.9) | 142.4 (78.6) | <0.001 |
Mean sodium, mmol/l (SD) | 136.8 (11.3) | 136.3 (11.6) | 137.6 (10.5) | 0.208 | 137.3 (10.8) | 135.9 (13.5) | 137.4 (8.9) | 136.5 (11.4) | 0.875 |
Mean potassium, mmol/l (SD) | 5.3 (1.2) | 5.3 (1.2) | 5.3 (1.2) | 0.774 | 5.3 (1.2) | 5.4 (1.3) | 5.2 (1.1) | 5.3 (1.1) | 0.890 |
Mean chlorine,mmol/l (SD) | 100.8 (13.7) | 100.4 (14.3) | 101.6 (12.4) | 0.347 | 101.2 (8.1) | 100.3 (14.8) | 100.6 (15.5) | 101.2 (14.7) | 0.938 |
Mean Ca2+,mg/l (SD) | 80.0 (14.6) | 80.1 (15.2) | 80.0 (13.4) | 0.842 | 75.6 (17.0) | 81.0 (13.0) | 79.7 (12.5) | 83.7 (12.9) | 0.001 |
Mean phosphate,mg/l (SD) | 70.5 (37.4) | 70.2 (32.9) | 71.1 (45.0) | 0.829 | 73.0 (36.1) | 73.9 (42.5) | 70.1 (29.5) | 65.6 (40.9) | 0.119 |
Dialysis start, n (%) | 677 (78.4) | 449 (78.8) | 228 (77.8) | 0.746 | 173 (84.4) | 178 (81.7) | 168 (76.0) | 158 (72.1) | 0.009 |
Background nephropathy, n (%) | 0.021 | <0.001 | |||||||
Hypertension | 267 (30.9) | 190 (33.3) | 77 (26.3) | 26 (12.7) | 86 (39.4) | 75 (33.9) | 80 (36.6) | ||
Diabetes | 137 (15.9) | 100 (17.5) | 37 (12.6) | 5 (2.4) | 20 (9.2) | 63 (28.5) | 49 (22.4) | ||
Hypertension and diabetes | 65 (7.5) | 44 (7.7) | 21 (7.2) | 4 (2.0) | 5 (2.3) | 24 (10.9) | 32 (14.6) | ||
Chronic glomerulonephritis | 136 (15.8) | 82 (14.4) | 54 (18.4) | 98 (47.8) | 22 (10.1) | 10 (4.5) | 6 (2.7) | ||
HIV | 57 (6.6) | 30 (5.3) | 27 (9.2) | 21 (10.2) | 20 (9.2) | 11 (5.0) | 5 (2.3) | ||
Others | 74 (8.6) | 48 (8.4) | 26 (8.9) | 12 (5.9) | 20 (9.2) | 21 (9.5) | 21 (9.6) | ||
Unknown | 127 (14.7) | 76 (13.3) | 51 (17.4) | 39 (19.0) | 45 (20.6) | 17 (7.7) | 26 (11.9) | ||
Median Charlson Score (Q1-Q3) | 3 [2-4] | 3 [2-4] | 3 [2-4] | 0.312 | 2 [2] | 2 [2] | 3 [3] | 4 [4,5] | <0.001 |