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Table 1 Baseline characteristics of SHARP patients included in the cost analysis

From: What is the impact of chronic kidney disease stage and cardiovascular disease on the annual cost of hospital care in moderate-to-severe kidney disease?

 

By baseline CKD stage 1

Overall

 

CKD 1-3B (eGFR: ≥30) 2

CKD 4 (eGFR: ≥15, <30)

CKD 5 (eGFR: <15 not on dialysis)

On dialysis

 

Number of patients

1,494

2,228

1,017

2,498

7,246

Men

1,078 (72%)

1,368 (61%)

599 (59%)

1,600 (64%)

4,652 (64%)

Age (years)

62 (11)

65 (12)

63 (12)

61 (12)

63 (12)

Prior vascular disease

189 (13%)

350 (16%)

147 (14%)

428 (17%)

1,116 (15%)

Prior diabetes mellitus

268 (18%)

454 (20%)

169 (17%)

546 (22%)

1,439 (20%)

Current smoker

205 (14%)

276 (12%)

133 (13%)

432 (17%)

1,048 (14%)

Body-mass index (kg/m2)

28.4 (5.3)

28.2 (5.8)

27.5 (5.5)

27.0 (5.9)

27.8 (5.7)

Diastolic blood pressure (mm Hg)

80 (13)

79 (13)

80 (12)

77 (13)

79 (13)

Systolic blood pressure (mm Hg)

138 (20)

138 (20)

141 (20)

137 (24)

138 (21)

Total cholesterol (mmol/L)

5.1 (1.1)

5.1 (1.1)

4.9 (1.2)

4.6 (1.2)

4.9 (1.2)

LDL cholesterol (mmol/L)

3.0 (0.8)

2.9 (0.8)

2.8 (0.9)

2.6 (0.9)

2.8 (0.9)

HDL cholesterol (mmol/L)

1.2 (0.3)

1.2 (0.3)

1.1 (0.3)

1.1 (0.4)

1.1 (0.3)

Triglycerides (mmol/L)

2.3 (1.6)

2.3 (1.4)

2.2 (1.4)

2.3 (1.9)

2.3 (1.6)

Renal status

     

 On dialysis

-

-

-

2,498 (100%)

2,498 (34%)

  Hemodialysis

-

-

-

2,076 (83%)

2,076 (29%)

  Peritoneal dialysis

-

-

-

422 (17%)

422 (6%)

 Not on dialysis

1,494 (100%)

2,228 (100%)

1,017 (100%)

-

4,739 (65%)

Estimated glomerular filtration rate (mL/min/1.732)

37.6 (6.5)

22.5 (4.3)

10.8 (2.7)

-

24.8 (10.9)

Urinary albumin:creatinine ratio (mg/g)3

     

 Median (IQR)

75 (16–328)

155 (36–592)

397 (124–1,204)

-

156 (35–626)

 <30

459 (36%)

426 (22%)

62 (7%)

-

947 (23%)

 ≥30, ≤ 300

496 (38%)

820 (42%)

332 (37%)

-

1,648 (40%)

 >300

336 (26%)

722 (37%)

511 (56%)

-

1,569 (38%)

 Not available

203

260

112

-

584

Region of recruitment

     

 Europe

1,022 (68%)

1,546 (69%)

730 (72%)

1,779 (71%)

5,083 (70%)

 Australasia

260 (17%)

446 (20%)

187 (18%)

408 (16%)

1,302 (18%)

 North America

212 (14%)

236 (11%)

100 (10%)

311 (12%)

861 (12%)

  1. Data are n (%), mean (SD) or median (IQR); CKD = chronic kidney disease.
  2. 19 patients who received a transplant prior to randomization were excluded from the tabulation by baseline CKD stage.
  3. 2Predominantly CKD stage 3B (eGFR ≥30 to <45 ml/min/1.73m2).
  4. 3Percentages exclude patients for whom data were not available.