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Table 1 Reduction ratios (%) for different protein-bound solutes in SHD and MPHD

From: Protein-bound solute removal during extended multipass versus standard hemodialysis

Solute

SHD

MPHD

 

0-240 min

0-240 min

240-480 min

0-480 min

Total PCG

81 ± 7

51 ± 5

9 ± 9†

55 ± 6*†

Total HA

68 ± 10

42 ± 7

1 ± 37†

43 ± 16*

Total IAA

46 ± 8

25 ± 5

9 ± 13†

32 ± 8*

Total IS

41 ± 11

14 ± 6

10 ± 12

23 ± 11*†

Total PCS

37 ± 9

10 ± 9

6 ± 18

16 ± 15*

Free PCG

84 ± 5

51 ± 5

10 ± 10†

56 ± 6*†

Free HA

78 ± 8

45 ± 11

−5 ± 38†

44 ± 16*

Free IAA

67 ± 28

33 ± 13

8 ± 21†

39 ± 18*

Free IS

59 ± 17

−7 ± 33

7 ± 43

−2 ± 55*

Free PCS

74 ± 11

−1 ± 44

7 ± 39

7 ± 51*

  1. SHD: standard hemodialysis; MPHD: multipass hemodialysis; PCG: p-cresylglucuronide; HA: hippuric acid; IAA: indole acetic acid; IS: indoxyl sulfate; PCS: p-cresylsulfate.
  2. *P < 0.05 versus SHD; †P < 0.05 versus MPHD0-240min.