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Table 2 Extraction ratios (%) at 60 min during SHD and MPHD for total and free fractions of different protein-bound solutes

From: Protein-bound solute removal during extended multipass versus standard hemodialysis

Solute

SHD

MPHD

SHD/MPHD

Total PCG

73 ± 15

53 ± 8*

1.4

Total HA

54 ± 10

31 ± 19*

1.7

Total IAA

29 ± 8

16 ± 8*

1.8

Total IS

13 ± 5

5 ± 5*

2.9

Total PCS

11 ± 6

3 ± 5*

3.9

Free PCG

78 ± 10

55 ± 9*

1.4

Free HA

65 ± 11

43 ± 8*

1.5

Free IAA

49 ± 23

31 ± 12*

1.6

Free IS

36 ± 9

17 ± 10*

2.1

Free PCS

38 ± 15

15 ± 10*

2.5

  1. SHD: standard hemodialysis; MPHD: multipass hemodialysis; PCG: p-cresylglucuronide; HA: hippuric acid; IAA: indole acetic acid; IS: indoxyl sulfate; PCS: p-cresylsulfate.
  2. *P < 0.05 versus SHD.
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BMC Nephrology

ISSN: 1471-2369

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