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Table 4 Weekly total solute removal (mg) for 3 times 4 h SHD, 6 times 2 h MPHD, 6 times 4 h MPHD, and 6 times 8 h MPHD for different protein-bound solutes

From: Protein-bound solute removal during extended multipass versus standard hemodialysis

Solute

3x4 h SHD

6x2 h MPHD

6x4 h MPHD

6x8 h MPHD

Total PCG

480 ± 458

498 ± 452

655 ± 592*

729 ± 650*†

Total HA

1985 ± 2010

1338 ± 1296*

1738 ± 1688

2104 ± 2096†

Total IAA

83 ± 101

69 ± 70

89 ± 90

98 ± 105*

Total IS

478 ± 291

308 ± 232*

388 ± 314*

406 ± 320*

Total PCS

306 ± 183

199 ± 112*

246 ± 148*

241 ± 155**

  1. SHD: standard hemodialysis; MPHD: multipass hemodialysis; PCG: p-cresylglucuronide; HA: hippuric acid; IAA: indole acetic acid; IS: indoxyl sulfate; PCS: p-cresylsulfate.
  2. *P < 0.05 versus 3x4 h SHD; **P = 0.57 versus 3x4 h SHD; †P < 0.05 versus 6x4 h MPHD.