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Table 1 Characteristics of the study population

From: A prospective observational study comparing a non-operator dependent automatic PWV analyser to pulse pressure, in assessing arterial stiffness in hemodialysis

  Dialysis Group (N = 143) Control Group (N = 100) P -value
Age yr 71.3 ± 11.9 72.0 ± 8.9 ns
Male sex no. (%) 77 (53.8) 71 (71.0) <0.01
Coexisting conditions no. (%)
Smoker 47 (32.9) 45 (45.0) ns
pack years 44.4 ± 19.6 57.6 ± 23.1 ns
Hypertension 130 (90.9) 86 (86.0) ns
Diabetes 54 (37.8) 32 (32.0) ns
HbA1c % 6.9 ± 1.6 6.6 ± 1.8 ns
Dyslipidaemia 86 (60.1) 52 (52.0) ns
Cholesterol totalmmol/L 4.5 ± 1.2 4.6 ± 1.5 ns
LDL cholesterolmmol/L 2.7 ± 1.0 3.1 ± 1.3 ns
CVD 83 (58.0) 53 (53.0) ns
eGFR (EPI) ml/min/1.73 m2 <15 67.2 ± 23.9 -
Proteinuria mg/mmol No data 23 ± 47 -
Anti-hypertensive therapy no. (%)
RAAS-inhibitors 64 (44.8) 64 (64.0) <0.01
Calcium-antagonists 48 (33.6) 30 (30.0) ns
Beta-blockers 61 (42.7) 35 (35.0) ns
Alpha-blockers 29 (20.3) 4 (4.0) <0.01
Diuretics 72 (50.3) 43 (43.0) ns
Follow-up months 16.4 ± 7.5 0 -
Duration of dialysis months 40.3 ± 35.2 - -
Kt/V 1.47 ± 0.33 - -
Haemodynamics measuresmean ± SD
Systolic Pressure (peripheral)mmHg 126.2 ± 22.9 128.7 ± 17.5 ns
Diastolic Pressure (peripheral)mmHg 74.8 ± 14.0 78.4 ± 12.5 <0.05
Systolic Pressure (central)mmHg 114.8 ± 21.1 117.8 ± 16.6 ns
Diastolic Pressure (central)mmHg 76.5 ± 14.1 79.9 ± 12.6 0.05
Peripheral resistancess*mmHg/ml 1.4 ± 0.3 1.4 ± 0.2 ns
Cardiac output l/min 3.8 ± 0.6 3.9 ± 0.6 ns
Pulse Pressure mmHg 51.3 ± 15.1 50.3 ± 12.0 ns
Diabetics 53.5 ± 10.5 54.6 ± 12.9 ns
non-Diabetics 50.0 ± 17.2 48.3 ± 11.2 ns
CVD 50.8 ± 14.4 49.5 ± 12.1 ns
non-CVD 52.0 ± 16.2 51.1 ± 12.0 ns
Alx@75 % 25.1 ± 10.6 29.6 ± 10.0 <0.01
Refl. Coef. % 63.1 ± 7.5 64.8 ± 6.3 ns (0.06)
MobPWV adjusted m/s 7.6 ± 2.1 6.4 ± 1.5 <0.01
Diabetics 7.9 ± 1.9 6.5 ± 1.5 <0.01
non-Diabetics 7.5 ± 2.2 6.4 ± 1.6 <0.01
CVD 7.8 ± 2.2 6.7 ± 1.4 <0.01
non- CVD 7.4 ± 2.0 6.1 ± 1.6 <0.01
MobPWV unadjusted m/s 10.6 ± 2.2 10.5 ± 1.7 ns
Diabetics 10.9 ± 2.0 10.7 ± 1.7 ns
non-Diabetics 10.5 ± 2.3 10.4 ± 1.7 ns
CVD 10.7 ± 2.3 10.8 ± 1.7 ns
non-CVD 10.5 ± 2.1 10.2 ± 1.6 ns
Labor resultsmean ± SD
Ionized calcium mmol/l 1.15 ± 0.09 No data  
Diabetics 1.14 ± 0.08   
non-Diabetics 1.16 ± 0.09   
CVD 1.15 ± 0.09   
non-CVD 1.15 ± 0.09   
PTH pmol/l 28.9 ± 21.0 No data  
Diabetics 26.1 ± 20.8   
non-Diabetics 30.6 ± 21.0   
CVD 28.8 ± 22.6   
non-CVD 29.0 ± 18.7   
Phosphate mmol/L 1.59 ± 0.44   
Bicarbonate mmol/L 18.7 ± 8.1   
  1. MobPWV = PWV obtained by Mobil-O-Graph (adjusted by systolic blood pressure and unadjusted); Alx@75 = augmentation index corrected at 75 beats per minute; Refl. Coef. = reflection coefficient; CVD = cardiovascular disease (coronary heart disease and/or cerebrovascular disease and/or peripheral arterial disease); CHF = congestive heart failure; BMI = body-mass Index; RAAS = renin-angiotensin-aldosterone-system; DBW = dry body weight; ns = non-significant.
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