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Table 4 Magnetic resonance imaging (MRI) Sequences performed in the NiCK study

From: Design and methods of the NiCK study: neurocognitive assessment and magnetic resonance imaging analysis of children and young adults with chronic kidney disease

Name Sequence parameters
3D T1 MPRAGE TR = 1.79 s, TE = 3.06 ms, TI = 1.050 s, FoV = 250 × 250 mm2, flip angle = 10°, voxel size = 1 × 1 × 1 mm3
pCASL 2D GE EPI TR = 4 s, TE = 12 ms, FoV 220 × 220 mm2, flip angle = 90°, voxel size = 3.4 × 3.4 × 5.0 mm3, labeling duration 1.5 s, postlabeling delay 1.2 s, 40 label/control pairs
T2 FLAIR TR = 9 s, TE = 76 ms, TI = 2.5 s, FoV = 220 × 220 mm2, flip angle = 146°, voxel size = 0.9 × 0.9 × 2 mm3
T1 FLASH TR = 300 ms, TE = 2.46 ms, FoV = 225 × 225 mm2, flip angle = 60°, voxel size = 0.9 × 0.9 × 3 mm3
GRE Field Mapping TR = 499 ms, TE1 = 5.19 ms, TE2 = 7.65 ms, FoV = 192 × 192 mm2, flip angle = 60°, voxel size = 3 × 3 × 3 mm3
Resting fMRI/GE EPI TR = 3 s, TE 30 ms, FoV = 192 × 192 mm2, flip angle = 90°, voxel size = 3 × 3 × 3 mm3 isotropic, 102 volumes
DTI SE EPI TR = 11 s, TE = 76.4 ms, b = 0 and 1000 s/mm2, 30 directions, FoV = 256 × 256 mm2, voxel size = 2 × 2 × 2 mm3
Proton Density/T2 MRI TR = 6.22 s, TE1= 14 ms, TE2 = 98 ms, FoV = 256 × 256 mm2, flip angle = 150°, voxel size = 1 × 1 × 2 mm3
  1. MPRAGE, magnetization prepared rapid acquisition gradient echo; pCASL, pseudocontinuous arterial spin labeling; GE EPI, gradient-echo echo-planar imaging; FLAIR, fluid-attenuated inversion recovery; FLASH, fast low angle shot; GRE, gradient recalled echo; fMRI, functional MRI; DTI, diffusion tensor imaging; PD, proton density; T1, T2, weighting of applied MRI sequence; TR, repetition time; TE, echo time; TI, inversion time; FoV, field of view.