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Table 2 Medians and inter-quartile range of inflammatory biomarkers according to chronic kidney disease status

From: Association of C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 with chronic kidney disease

Inflammatory Biomarkers Unadjusted median (IQR) Multivariable-adjusted median (IQR)a
CKD patients (n = 201) Non-CKD controls (n = 201) P-value for difference CKD patients (n = 201) Non-CKD controls (n = 201) P-value for difference
CRP, mg/L (IQR) 2.80 (1.13, 5.61) 1.49 (0.75, 3.65) <0.0001 2.91 (1.47, 5.24) 1.91 (0.99, 3.79) 0.39
TNF-α, pg/mL (IQR) 1.82 (1.5, 2.51) 1.27 (0.99, 1.81) <0.0001 1.86 (1.51, 2.63) 1.26 (1.01, 1.98) <0.0001
IL-6, pg/mL (IQR) 2.46 (1.32, 4.54) 1.24 (0.88, 2.2) <0.0001 2.53 (1.49, 4.42) 1.39 (0.95, 2.15) 0.04
  1. IQR = inter-quartile range; CRP = C-reactive protein; TNF-α = tumor necrosis factor alpha; IL-6 = interleukin 6
  2. aAdjusted for age, gender, race, high-school education, physical activity, current cigarette smoking, weekly alcohol drinking, body-mass index, LDL-cholesterol, plasma glucose, systolic blood pressure, history of cardiovascular disease, antihypertensive treatment, antidiabetic treatment, lipid lowering treatment, and aspirin use