Table 3 Measured protein nitrogen appearance, nutritional and quality of life measures, plasma inflammatory markers and bicarbonate levels and residual renal function at baseline, 12 and 24 weeks^a

PNA (g/kg/day)

1.12 ± 0.32

1.04 ± 0.30

1.18 ± 0.35

MAMC (cm)

26.5 ± 3.9

26.2 ± 4.0

26.6 ± 4.3

Plasma albumin (g/dL)

3.76 ± 0.31

3.79 ± 0.33

3.75 ± 0.35

Body Mass Index (kg/m²)

29.2 ± 6.9

29.0 ± 6.9

28.8 ± 5.6

SF12 - Physical Health Composite Scale Scores

29.3 ± 9.6

30.6 ± 9.9

29.2 ± 9.0

SF12 - Mental Health Composite Scale Scores

51.4 ± 11.3

50.9 ± 11.1

50.6 ± 13.1

Plasma hsCRP (mg/L)

16.0 (7.7, 25.1)

10.9 (6.4, 25.3)

14.0 (7.9, 38.0)

Plasma TNF-α (pg/ml)

15.4 (9.1, 43.0)

17.4 (11.0, 41.8)

19.3 (12.4, 94.4)

Plasma IL6 (pg/ml)

10.7 (5.1, 20.2)

13.2 (8.9, 19.9)

12.8 (5.0, 35.5)

Plasma bicarbonate (mmol/L)

24.2 ± 4.4

26.1 ± 3.1

26.3 ± 3.4

% with residual renal function

34.7

26.1

20.5

24-h urine volume in those with residual renal function (ml/d)

648.0 ± 374.3

562.5 ± 371.6

643.9 ± 331.3