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Fig. 3 | BMC Nephrology

Fig. 3

From: Increased urinary Angiotensinogen/Creatinine (AGT/Cr) ratio may be associated with reduced renal function in autosomal dominant polycystic kidney disease patients

Fig. 3

Urinary AGT/Cr and PRA Levels According to CKD Stages and Hypertension. As a marker of intrarenal RAS activation, we measured urinary AGT/Cr and compared with PRA level, a marker of systemic RAS activation. Both urinary AGT/Cr and PRA were elevated in hypertensive subjects compared to normotensive subjects (P > 0.05). Among hypertensive subjects, urinary AGT/Cr was significantly increased in the advanced CKD stages (III-V, gray bar) compared to early CKD stages (I-II, white bar)(28.6 ± 60.3 vs. 93.2 ± 139.3 μg/g, P < 0.001). In contrast, PRA levels were not statistically different between CKD stage groups. AGT, angiotensinogen; CKD, chronic kidney disease; Cr, creatinine; PRA, plasma renin activity

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BMC Nephrology

ISSN: 1471-2369

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