Table 1 Baseline characteristics of patients with ANCA-associated vasculitis who required hemodialysis at the time of kidney biopsy stratified by age of vasculitis diagnosis

Age at diagnosis, years (mean ± SD^a)

41 ± 11

71 ± 7

<0.001

Female

8 (67 %)

7 (39 %)

0.136

African-American

4 (30 %)

2 (11 %)

0.136

Diagnosis

   Granulomatosis with polyangiitis

8 (67 %)

10 (56 %)

0.543

   Microscopic polyangiitis

4 (33 %)

8 (44 %)

PR3-ANCA positive^b

6 (67 %)

8 (50 %)

0.420

MPO-ANCA positive^b

3 (33 %)

8 (50 %)

Peak serum creatinine, mg/dL (mean ± SD^a)

5.8 ± 2.5

8.2 ± 4.4

0.150

Normal glomeruli, % (mean ± SD^a)

21.5 ± 18.1

27.4 ± 23.8

0.432

Renal histopathologic class

   Crescentic

4 (34 %)

4 (22 %)

   Focal

1 (8 %)

3 (17 %)

   Mixed

6 (50 %)

9 (50 %)

   Sclerotic

1 (8 %)

2 (11 %)