Table 1 Characteristics of Jackson Heart Study participants with and without chronic kidney disease
No CKD | CKD | p-value | |
|---|---|---|---|
(n = 849) | (n = 173) | ||
Age, years | 58.9 (0.4) | 60.8 (0.9) | 0.041 |
Female gender, % | 68.3 | 65.1 | 0.452 |
Less than high school education, % | 18.1 | 26.7 | 0.022 |
Low income, % | 10.8 | 15.6 | 0.142 |
Diabetes, % | 21.2 | 40.6 | <0.001 |
History of stroke, % | 2.9 | 8.8 | 0.002 |
History of myocardial infarction, % | 4.1 | 7.5 | 0.074 |
Current smoking, % | 5.3 | 7.4 | 0.329 |
Waist circumference, cm | 99.1 (0.5) | 104.5 (1.3) | <0.001 |
Total cholesterol, mg/dL | 200.7 (1.4) | 205.0 (3.5) | 0.242 |
HDL-cholesterol, mg/dL | 54.1 (0.5) | 51.5 (1.0) | 0.043 |
C-reactive protein > 3 mg/L, % | 46.7 | 52.1 | 0.213 |
Mean clinic SBP, mmHg | 126.0 (0.6) | 132.9 (1.6) | <0.001 |
Mean clinic DBP, mmHg | 77.3 (0.4) | 77.1 (0.9) | 0.781 |
Mean 24-h SBP, mmHg | 125.0 (0.4) | 132.7 (1.4) | <0.001 |
Mean 24-h DBP, mmHg | 73.8 (0.3) | 76.2 (0.9) | 0.004 |
eGFR, mL/min/1.73 m2 | 94.4 (0.6) | 77.7 (2.4) | <0.001 |
Albumin-to-creatinine ratio, mg/g | 5.5 (3.7, 9.4) | 55.3 (22.9, 125.5) | <0.001 |
Antihypertensive medication use, % | |||
Aldosterone antagonist | 1.6 | 4.9 | 0.073 |
Alpha blocker | 11.6 | 16.9 | 0.152 |
ACE inhibitor | 35.8 | 47.0 | 0.035 |
Angiotensin II receptor blocker | 12.2 | 13.3 | 0.753 |
Beta blocker | 24.1 | 18.6 | 0.234 |
Calcium channel blocker | 32.6 | 47.2 | 0.008 |
Diuretic | 65.6 | 65.4 | 0.971 |
Renin inhibitor | NA | NA | --- |
Vasodilator | 0.8 | 1.0 | 0.839 |