Skip to main content

Table 2 Association of chronic kidney disease status, albumin-to-creatinine ratio, and estimated glomerular filtration rate with measures of systolic blood pressure variability

From: Association between 24-hour blood pressure variability and chronic kidney disease: a cross-sectional analysis of African Americans participating in the Jackson heart study

Chronic kidney disease status

Blood pressure variability measure

No CKD

CKD

p-value

(n = 849)

(n = 173)

Day-night standard deviation, mmHg

   

Mean ± standard error

9.1 ± 0.1

10.2 ± 0.2

<0.001

Age, sex adjusted

0 (ref)

0.98 (0.59, 1.38)

<0.001

Multivariable adjusted 1a

0 (ref)

0.64 (0.19, 1.09)

0.005

Multivariable adjusted 2b

0 (ref)

0.31 (−0.12, 0.74)

0.162

Average real variability, mmHg

   

Mean ± standard error

8.6 ± 0.1

9.2 ± 0.2

0.001

Age, sex adjusted

0 (ref)

0.52 (0.18, 0.86)

0.003

Multivariable adjusted 1a

0 (ref)

0.32 (−0.09, 0.72)

0.125

Multivariable adjusted 2b

0 (ref)

0.08 (−0.31, 0.46)

0.695

Albumin-to-creatinine ratio, mg/g

Blood pressure variability measure

ACR < 30

ACR ≥ 30

p-value

(n = 885)

(n = 137)

Day-night standard deviation, mmHg

   

Mean ± standard error

9.2 ± 0.1

10.2 ± 0.3

<0.001

Age, sex adjusted

0 (ref)

1.09 (0.65, 1.53)

<0.001

Multivariable adjusted 1a

0 (ref)

0.85 (0.33, 1.37)

0.001

Multivariable adjusted 2b

0 (ref)

0.35 (−0.16, 0.85)

0.179

Average real variability, mmHg

   

Mean ± standard error

8.7 ± 0.1

9.2 ± 0.2

0.01

Age, sex adjusted

0 (ref)

0.57 (0.18, 0.95)

0.004

Multivariable adjusted 1a

0 (ref)

0.41 (−0.06, 0.89)

0.085

Multivariable adjusted 2b

0 (ref)

0.05 (−0.41, 0.50)

0.844

Estimated glomerular filtration rate, mL/min/1.73 m 2

Blood pressure variability measure

eGFR ≥ 60

eGFR < 60

p-value

(n = 960)

(n = 62)

Day-night standard deviation, mmHg

   

Mean ± standard error

9.3 ± 0.1

10.4 ± 0.4

<0.001

Age, sex adjusted

0 (ref)

0.58 (−0.04, 1.20)

0.066

Multivariable adjusted 1a

0 (ref)

0.24 (−0.39, 0.86)

0.455

Multivariable adjusted 2b

0 (ref)

0.17 (−0.42, 0.77)

0.565

Average real variability, mmHg

   

Mean ± standard error

8.7 ± 0.1

9.5 ± 0.2

0.004

Age, sex adjusted

0 (ref)

0.27 (−0.24, 0.78)

0.296

Multivariable adjusted 1a

0 (ref)

−0.01 (−0.54, 0.52)

0.981

Multivariable adjusted 2b

0 (ref)

−0.05 (−0.56, 0.46)

0.842

  1. CKD chronic kidney disease, ACR albumin-to-creatinine ratio, eGFR estimated glomerular filtration rate
  2. aAdjusted for age, sex, education, income, smoking status, waist circumference, diabetes, history of stroke, history of myocardial infarction, total cholesterol, high-density lipoprotein cholesterol, c-reactive protein, statin use, and antihypertensive medication use
  3. bAdjusted for above model 1 plus mean 24-h systolic blood pressure
Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us