Parameter | End stage renal disease | P value | |
---|---|---|---|
No | Yes | ||
Patients number | 38 | 13 | |
General | |||
Gender (% Male) | 47 | 69 | 0.01 |
Age (years) | 63 [53; 69] | 51 [35; 57] | 0.01 |
Vasculitis | |||
PR3-ANCA (%) | 64 | 36 | 0.37 |
MPO-ANCA (%) | 78 | 22 | |
Severe lung hemorrhage (%) | 24 | 39 | 0.30 |
BVAS | 15 [13; 21] | 16 [15; 21] | 0.63 |
Response to induction therapy | 97 % | 15 % | <0.0001 |
Inflammation | |||
Hemoglobin (g/dL) | 9.0 [7.8; 10.0] | 8.0 [6.0; 9.0] | 0.07 |
WBC (per mm3) | 9700 [7800; 14200] | 8000 [6300; 12500] | 0.17 |
ESR (mm/1 h) | 99 [65; 115] | 110 [82; 140] | 0.28 |
Fibrinogen (mg/dL) | 717 [578; 800] | 720 [612; 820] | 0.97 |
Albumin (g/dL) | 3.8 [3.2; 4.0] | 3.5 [3.1; 3.9] | 0.25 |
Kidney | |||
Histopathologic class | |||
Crescentic (%) | 46 | 67 | 0.28 |
Focal (%) | 7 | 0 | |
Mixed (%) | 33 | 29 | |
Sclerotic (%) | 13 | 5 | |
Creatinine (mg/dL) | 4.0 [2.9; 5.8] | 9.0 [4.5; 12.0] | 0.006 |
Proteinuria (g/day) | 0.6 [0.4; 1.5] | 2.3 [1.2; 3.0] | 0.007 |
Hematuria (per mm3) | 210 [150; 290] | 460 [230; 980] | 0.003 |
Dialysis at presentation (%) | 8 | 62 | <0.0001 |