Skip to main content

Table 5 Patients’ characteristics according to outcome

From: ANCA positive crescentic glomerulonephritis outcome in a Central East European cohort: a retrospective study

Parameter

Patients’ death

P value

 

No

Yes

 

Patients number

51

24

 

General

   

Gender (% Male)

53

38

0.21

Age (years)

60 [50; 68]

63 [60; 68]

0.14

Vasculitis

   

MPO-ANCA (%)

65

35

0.31

PR3-ANCA (%)

78

22

Severe lung hemorrhage (%)

29

39

0.39

BVAS

15 [14; 21]

20 [17; 21]

0.01

Response to induction therapy

76 %

25 %

<0.0001

Inflammation

   

Hemoglobin (g/dL)

8.6 [7.7; 9.9]

8.5 [7.4; 9.8]

0.79

WBC

9400 [7600; 13900]

10600 [7800; 18400]

0.21

ESR

100 [78; 120]

80 [61; 120]

0.20

Fibrinogen

720 [578; 820]

645 [525; 750]

0.15

Serum albumin

3.7 [3.2; 4.0]

3.2 [2.8; 3.6]

0.008

Kidney

   

Histopathologic class

   

Crescentic (%)

49

58

0.5

Focal (%)

4

8

Mixed (%)

33

29

Sclerotic (%)

14

4

Serum creatinine (mg/dL)

4.7 [3.0; 7.4]

6.9 [4.1; 8.0]

0.06

Proteinuria

0.9 [0.5; 2.2]

0.8 [0.6; 2.2]

1.00

Hematuria

230 [180; 670]

365 [240; 1600]

0.008

Dialysis at presentation (%)

22

38

0.15

  1. Values are median [quartile 1; quartile 3] if not otherwise specified
  2. PR3-ANCA patients positive for anti-proteinase 3 antibodies, MPO-ANCA patients positive for anti-myeloperoxidase antibodies, BVAS Birmingham Vasculitis Activity Score, WBC white blood cells, ESR erythrocite sedimentation rate