Skip to main content

Table 5 Cross sectional analysis of albumin tertiles and select metabolites

From: Cross-sectional examination of metabolites and metabolic phenotypes in uremia

  1 2 3 P
kynurenine 425 998 (298 054, 535 460) 478 927 (395 468, 596 735) 552 251 (433 248, 679 481) 1.8E-4*
tryptophan 273 066 (223 467, 413 194) 315 338 (255 914, 423 927) 393 551 (301 885, 501 066) 2.5E-4*
creatine 2 157 292 (1 397 576, 3 355 087) 1 907 461 (1 145 455, 2 791 140) 1 570 693 (1 182 023, 2 037 120) 4.9E-3
indoxylsulfate 42 510 713 (24 175 943, 58 375 318) 55 564 881 (34 527 474, 67 400 369) 57 398 073 (33 359 446, 80 148 935) 1.3E-2
12:0 carnitine 28 261 (18 195, 40 622) 30 496 (18 540, 44 940) 36 915 (24 245, 50 553) 2.7E-2
aspartate 36 448 (25 083, 49 840) 34 626 (24 685, 48 518) 26 533 (20 120, 36 067) 1.9E-3
thyroxine 2 332 (1 929, 2 738) 2 523 (1 879, 2 916) 2 712 (2 115, 3 244) 1.8E-2
indolelactate 12 722 (8 573, 19 334) 15 627 (11 171, 22 311) 16 269 (11 922, 22 700) 3.6E-2
BAIBA 46 979 (27 423, 106 593) 42 313 (24 146, 80 713) 34 051 (23 583, 57 272) 1.0E-1
alanine 1 280 822 (985 715, 1 604 978) 1 249 845 (1 028 428, 1 494 869) 1 337 859 (1 117 636, 1 758 661) 6.9E-2
10:0 carnitine 33 566 (21 210, 61 857) 48 413 (25 775, 68 324) 47 884 (31 469, 72 628) 5.8E-2
SDMA 896 522 (765 176, 1 090 288) 925 219 (772 578, 1 063 241) 824 248 (730 601, 974 498) 5.2E-2
hydroxyproline 235 578 (162 155, 374 510) 203 966 (149 720, 306 721) 198 496 (150 564, 259 207) 1.5E-1
GCDCAs 487 186 (203 751, 773 938) 421 065 (248 114, 748 019) 715 307 (356 712, 1 064 255) 1.4E-2
ADP 280 998 (155 075, 610 214) 539 330 (278 012, 877 605) 455 070 (164 681, 1 239 020) 1.2E-2
  1. Values are median peak area for the metabolites (quartile 1, quartile 3)
  2. *P-value significant at the Bonferroni adjusted level of 3.0 × 10−4