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Table 5 Cross sectional analysis of albumin tertiles and select metabolites

From: Cross-sectional examination of metabolites and metabolic phenotypes in uremia

 

1

2

3

P

kynurenine

425 998 (298 054, 535 460)

478 927 (395 468, 596 735)

552 251 (433 248, 679 481)

1.8E-4*

tryptophan

273 066 (223 467, 413 194)

315 338 (255 914, 423 927)

393 551 (301 885, 501 066)

2.5E-4*

creatine

2 157 292 (1 397 576, 3 355 087)

1 907 461 (1 145 455, 2 791 140)

1 570 693 (1 182 023, 2 037 120)

4.9E-3

indoxylsulfate

42 510 713 (24 175 943, 58 375 318)

55 564 881 (34 527 474, 67 400 369)

57 398 073 (33 359 446, 80 148 935)

1.3E-2

12:0 carnitine

28 261 (18 195, 40 622)

30 496 (18 540, 44 940)

36 915 (24 245, 50 553)

2.7E-2

aspartate

36 448 (25 083, 49 840)

34 626 (24 685, 48 518)

26 533 (20 120, 36 067)

1.9E-3

thyroxine

2 332 (1 929, 2 738)

2 523 (1 879, 2 916)

2 712 (2 115, 3 244)

1.8E-2

indolelactate

12 722 (8 573, 19 334)

15 627 (11 171, 22 311)

16 269 (11 922, 22 700)

3.6E-2

BAIBA

46 979 (27 423, 106 593)

42 313 (24 146, 80 713)

34 051 (23 583, 57 272)

1.0E-1

alanine

1 280 822 (985 715, 1 604 978)

1 249 845 (1 028 428, 1 494 869)

1 337 859 (1 117 636, 1 758 661)

6.9E-2

10:0 carnitine

33 566 (21 210, 61 857)

48 413 (25 775, 68 324)

47 884 (31 469, 72 628)

5.8E-2

SDMA

896 522 (765 176, 1 090 288)

925 219 (772 578, 1 063 241)

824 248 (730 601, 974 498)

5.2E-2

hydroxyproline

235 578 (162 155, 374 510)

203 966 (149 720, 306 721)

198 496 (150 564, 259 207)

1.5E-1

GCDCAs

487 186 (203 751, 773 938)

421 065 (248 114, 748 019)

715 307 (356 712, 1 064 255)

1.4E-2

ADP

280 998 (155 075, 610 214)

539 330 (278 012, 877 605)

455 070 (164 681, 1 239 020)

1.2E-2

  1. Values are median peak area for the metabolites (quartile 1, quartile 3)
  2. *P-value significant at the Bonferroni adjusted level of 3.0 × 10−4