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Table 7 Cross sectional analysis of systolic blood pressure tertiles and select metabolites

From: Cross-sectional examination of metabolites and metabolic phenotypes in uremia

  1 2 3 P
14:0 carnitine 10 549 (7 384, 17 510) 7 855 (6 040, 11 626) 6 824 (4 844, 9 486) 9.0E-6*
tryptophan 433 424 (297 696, 573 865) 366 630 (261 744, 444 478) 285 101 (229 380, 350 075) 1.2E-6*
18:1 carnitine 86 406 (56 919, 127 989) 70 273 (47 764, 105 108) 52 275 (32 871, 76 097) 8.7E-6*
18:2 carnitine 55 715 (35 972, 84 528) 44 392 (31 334, 69 607) 30 733 (21 812, 54 084) 5.5E-5*
3:0 carnitine 770 205 (556 166, 976 463) 604 794 (378 770, 724 282) 549 619 (381 463, 708 095) 5.4E-5*
deoxyadenosine 882 (605, 1 330) 831 (455, 1 011) 571 (441, 787) 7.5E-5*
16:1 carnitine 70 042 (50 052, 97 483) 53 904 (39 997, 77 945) 47 577 (36 257, 68 016) 4.2E-4
18:0 carnitine 12 434 (8 777, 17 403) 10 456 (7 790, 15 356) 8 806 (6 509, 12 276) 4.2E-4
carnitine 4 940 542 (4 375 772, 5 974 275) 4 311 636 (3 616 956, 4 936 736) 4 279 513 (3 743 960, 4 756 471) 2.1E-5*
12:0 carnitine 39 844 (22 621, 61 584) 33 433 (22 258, 39 850) 27 094 (17 488, 43 033) 8.5E-3
kynurenic acid 63 185 (35 805, 129 532) 86 131 (60 982, 133 796) 116 334 (67 598, 169 586) 9.4E-4
tyrosine 255 780 (216 337, 319 582) 231 195 (200 964, 273 325) 223 332 (177 881, 270 817) 8.4E-3
ADMA 309 751 (281 198, 370 574) 290 947 (261 258, 344 552) 284 594 (248 154, 328 619) 1.1E-2
taurocholate 103 888 (39 457, 284 746) 65 463 (26 657, 196 110) 59 392 (25 323, 157 090) 1.8E-2
cytidine 60 033 (36 540, 80 779) 51 105 (32 838, 73 636) 44 821 (26 784, 61 200) 2.1E-2
  1. Values are median peak area for the metabolites (quartile 1, quartile 3)
  2. *P-value significant at the Bonferroni adjusted level of 3.0 × 10−4