Skip to main content

Table 1 Demographics in AKI vs no-AKI according to different definitions

From: Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study

AKI definition

ΔADM > 0.3

  

ΔHIS > 0.3

  

ΔEST > 0.3

  

AKI/noAKI (n/%)

AKI (27/13.8)

no AKI (166/85.1)

p value

AKI(98/50.3)

no AKI (97/49.7)

p value

AKI (89/45.6)

no AKI (106/54.4)

p value

%male

66.7

61.4

0.6

67.3

57.7

0.17

65.2

60.4

0.49

Age(y)(mean/sd)

66.2(10.7)

60.7(15.6)

0.08

62.6(14.1)

60.2(15.8)

0.28

65.1(13.5)

58.2(15.5)

0.001

APACHE II

27(9)

22(9)

0.003

25(8)

19(9)

<0.001

25(8)

20(9)

<0.001

Ventilation(n/%)

25/92.6

80/48.2

<0.001

59/60.2

47/48.5

0.10

55/61.8

51/48.1

0.06

CKD(n/%)

7/25.9

23/13.9

0.11

18/18.4

12/12.4

0.25

25/28.1

5/4.7

<0.001

ICU admission serum creatinine (mg/dl)

1.29(0.66)

1.05(0.89)

0.01

1.67(1.25)

0.79(0.40)

<0.001

1.76(1.24)

0.80(0.39)

<0.001

Historical baseline creatinine (mg/dl)

0.98(0.41)

0.83(0.32)

0.18

0.88(0.37)

0.82(0.34)

0.52

0.98(0.35)

0.79(0.32)

0.001

RRT need(n/%)

14/51.9

13/7.8

<0.001

23/23.5

4/4.1

<0.001

24/27

3/2.8

<0.001

ICU LOS(d) in ICU survivors

15(22)

6(8)

0.009

6(9)

5(10)

0.34

7(9)

6(9)

0.24

ICU Mort(n/%)

12/44.4

31/18.7

0.003

25/25.5

20/20.6

0.42

22/24.7

23/21.7

0.62

Mort at three months(n/%)

13/48.1

46/27.7

0.03

32/32.7

29/39.9

0.68

30/33.7

31/29.2

0.50

Mort at 1 year(n/%)

17/63

66/39.8

0.024

42/42.9

43/44.3

0.84

41/46.1

44/41.5

0.52

Mort at 2 years(n/%)

17/63

79/47.6

0.14

47/48

51/52.6

0.52

46/48.3

51/51.9

0.62

  1. AKI Acute kidney injury, ΔADM > 0.3 = Serum creatinine increase > 0.3 mg/dl based on the difference between the value 24 h after admission and ICU admission, ΔHIS > 0.3 = Serum creatinine increase > 0.3 mg/dl based on the difference between the highest value during the first 24 h after ICU admission and a historical baseline value, ΔEST > 0.3 = Serum creatinine increase > 0.3 mg/dl based on the difference between the highest value during the first 24 h after ICU admission and an estimated baseline value, APACHE II Acute physiology and chronic health evaluation II score, CKD Chronic kidney disease, RRT Renal replacement therapy, ICU LOS Intensive care unit length of stay, Mort Mortality