Table 1 Baseline characteristics of the study subjects

Age at the transplantation^a

41.1 ± 11.9

42.8 ± 12.0

52.5 ± 10.4

57.7 ± 8.0

43.0 ± 12.3

<0.001^‡

Recipient’s sex (male, %)

54.7

57.4

67.2

79.2

57.2

0.003

Body weight (kg)^a

59.9 ± 10.7

61.4 ± 12.0

62.4 ± 11.0

64.8 ± 9.0

60.8 ± 11.2

0.003^‡

Height (cm)^a

164.2 ± 8.6

164.4 ± 8.8

164.4 ± 7.8

166.4 ± 7.4

164.4 ± 8.6

0.374

BMI (kg/m²)^a

22.1 ± 2.9

22.6 ± 3.5

23.0 ± 3.3

23.3 ± 2.6

22.4 ± 3.2

0.001^§

Current smoker (%)

10.6

9.1

23.3

6.4

9.8

<0.001

Past medical history

 Hypertension (%)

88.5

87.3

100.0

95.8

88.9

0.007

 DM (%)

14.1

21.5

49.3

64.6

20.4

<0.001

 Vascular diseases (%)^b

0.0

0.0

100.0

100.0

8.5

<0.001

 Dyslipidemia (%)

21.4

29.1

35.0

63.8

26.6

<0.001

Renal disease causing ESRD

0.033

 DM (%)

17.4

19.4

14.3

12.2

17.8

 Hypertension (%)

10.0

9.7

17.9

12.2

10.4

 Glomerulonephritis (%)

30.5

28.4

21.4

22.0

29.0

 PKD (%)

5.3

3.9

14.3

4.9

5.2

 Others (%)

36.8

38.6

32.1

48.7

37.6

Laboratory Findings

 Serum albumin (g/dl)^a

3.9 ± 0.4

3.4 ± 0.5

3.9 ± 0.3

3.3 ± 0.6

3.7 ± 0.5

<0.001^‡§

 CRP (mg/dl)^a

0.11 ± 0.11

0.97 ± 1.62

0.15 ± 0.13

1.25 ± 2.46

0.48 ± 1.17

<0.001^‡§

 Total cholesterol (mg/dl)^a

161.6 ± 37.5

155.7 ± 44.9

156.5 ± 38.4

151.6 ± 48.5

158.8 ± 40.9

0.044

 Triglyceride (mg/dl)^a

120.8 ± 67.2

125.9 ± 99.2

135.6 ± 89.5

133.6 ± 72.9

123.9 ± 81.1

0.419

LDL cholesterol (mg/dl)^a

91.5 ± 32.1

91.3 ± 31.8

87.2 ± 31.6

93.6 ± 43.2

91.3 ± 32.4

0.772

Intact PTH (pg/ml)^a

262.2 ± 312.8

238.7 ± 242.7

181.8 ± 183.8

249.7 ± 273.3

249.6 ± 279.4

0.29

CMV IgG positive (%)

93.1

96.0

92.9

96.3

94.8

0.475

Dialysis before TPL (%)

82.2

85.7

88.1

85.4

83.9

0.491

Preemptive TPL (%)

17.8

14.3

11.9

14.6

16.1

0.491

 HD:PD:both or switch (%)

60.7:18.4:3.1

57.8:24.0:3.9

63.3:18.3:6.5

68.8:14.6:2.0

60.0:20.4:3.5

0.308

 Dialysis duration (months)^a

26.7 ± 38.8

27.7 ± 38.0

38.4 ± 50.8

21.2 ± 27.7

27.4 ± 38.8

0.098

Donor information

 Deceased donor (%)

20.1

21.3

29.9

17.0

21.0

0.003

 Donor’s age (year)^a

40.2 ± 11.9

40.0 ± 12.4

41.7 ± 13.3

43.0 ± 12.8

40.3 ± 12.2

0.303

 Donor’s sex (male, %)

52.5

57.7

50.0

62.5

54.6

0.178

CMV IgG positive (%)

54.9

69.9

47.8

60.4

60.3

<0.001^§

TPL (KT only : SPK : Others, %)

89.1:3.1:7.8

91.4:4.8:3.8

85.1:4.5:10.4

89.6:2.1:8.3

89.8:3.8:6.4

0.053

Immunosuppressive agents

Steroid maintenance strategy (%)

92.6

89.5

100

85.7

90.9

0.625

CNI (CsA : Tacrolimus, %)

34.2:65.3

35.8:63.6

22.8:75.4

29.7:70.3

34.0:65.4

0.254

Antimetabolites (Aza : MMF, %)

6.5:88.1

10.2:79.4

10.5:80.7

8.6:82.9

8.0:84.6

0.095