A retrospective, longitudinal study estimating the association between interdialytic weight gain and cardiovascular events and death in hemodialysis patients

Table 2 Event count and incidence rates for outcomes of interest during the outcome period

Outcomes	Number of patients affected	Cumulative time at-risk, 1000 patient-years	Median time at-risk, days (p25, p50)	Incidence rate to first event, 1000 patient-years (95 % CI)
MI	2378	40.0	386 (221, 588)	59.5 (57.1–61.9)
HF	8802	36.2	340 (184, 543)	243 (238–248)
MACE^a	4314	40.1	387 (221, 589)	108 (105–111)
MACE+^b	11,488	35.4	330 (174, 533)	324 (381–330)
CV mortality^c	2294	41.1	398 (232, 602)	55.8 (53.6–58.2)
All-cause mortality	5818	41.1	398 (232, 602)	142 (138–145)

Abbreviations: p25 twenty-fifth quartile, p50 fiftieth quartile, CI confidence interval, CV cardiovascular, HF heart failure/volume overload, MACE major adverse cardiovascular event, MI myocardial infarction
^aDefined as nonfatal myocardial infarction, nonfatal ischemic stroke, or CV death
^bDefined as events comprising MACE as well as arrhythmia, nonfatal hemorrhagic stroke, or hospitalization for heart failure
^cDefined as death attributed to MI, atherosclerotic heart disease, cardiac arrhythmia, congestive HF, cardiomyopathy, cardiac arrest, valvular heart disease, pulmonary edema, or cerebrovascular accident including intracranial hemorrhage or ischemic brain damage/anoxic encephalopathy

ISSN: 1471-2369