Outcomes of sustained low efficiency dialysis versus continuous renal replacement therapy in critically ill adults with acute kidney injury: a cohort study

Table 4 Secondary outcomes, subgroup and sensitivity analyses

Secondary outcome	Unadjusted odds ratio (95 % CI)	Adjusted odds ratio (95 % CI)
RRT dependence at 30 days	1.27 (0.53–3.04)	1.36 (0.51–3.57)
Composite outcome: increase in SOFA score or death at 48 h	0.77 (0.44–1.35)	0.73 (0.40–1.34)
Subgroup analysis^a		Adjusted odds ratio (95 % CI)
SOFA score ≥16		1.44 (0.52–3.95)
SOFA score <16		0.84 (0.34–2.11)
Sensitivity analysis^b
SLED as predominant RRT modality		1.70 (0.75–3.82)
SLED as exclusive RRT modality in first 3 treatment sessions		1.36 (0.61–3.82)

^a30-day mortality for patients stratified by SOFA score
^b30-day mortality for patients with exposure defined by modality of majority of RRT treatment sessions received and patients with no change in RRT modality within the initial three RRT sessions

ISSN: 1471-2369