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Table 5 Ratio of SCr [the final evaluation pointa/W0 (week 0 of the treatment period)] analyzed by the ANCOVA model

From: Orally active prostacyclin analogue beraprost sodium in patients with chronic kidney disease: a randomized, double-blind, placebo-controlled, phase II dose finding trial

Treatment group

Number of patients

Least square mean of the ratio of SCr

Difference in the least square mean (versus placebo)

P-value*

Point estimate

SE

Point estimate

SE

Placebo

34

1.169

0.032

–

–

–

120 μg

32

1.069

0.033

0.100

0.045

0.0309

240 μg

36

1.064

0.031

0.105

0.044

0.0204

  1. aAt Week 28 of the treatment period or when treatment was discontinued
  2. *ANCOVA with baseline (SCr(R20)) as covariate