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Table 6 Review of systemic and kidney diseases associated with HLA type

From: Association between human leucocyte antigen subtypes and risk of end stage renal disease in Taiwanese: a retrospective study

Population

Study End point

Susceptibility

Protection

Reference

  

MHC class I

MHC class II

MHC class I

MHC class II

 

Taiwan

ESRD

DR3,DR11

 

DR8

*

Kuwaiti

ESRD

B8

 

A28

DR11

[42]

Saudi

ESRD

DQB1*03(8)

Cw2

 

[43]

 

Glomerulonephritis

     

China

 Poor renal outcome of ANCA related vasculitis

 

DRB1*04:05, DPB1*0402

  

[33]

China

 Cresentic GN in anti-GBM disease

 

DRB1*1501 DRB1*0404

  

[32]

Italy

 Churg-Strauss syndrome with renal involvement

 

DRB*04

  

[28]

United States

 Anti-GBM disease

 

DRB1*15 DRB1*04

 

DRB1*07

[23]

Taiwan

 Lupus nephritis

   

DRB1*1202

[31]

Italy

 Lupus nephritis

 

DRB1*1501, DQA1*0101

 

DQA1*0102

[26]

United States

 IgA nephropathy

B27

DR1

 

DR2

[44]

Japan

 IgA nephropathy

 

DR4

  

[14]

France

 IgA nephropathy

B35

   

[45]

Europe

 IgA nephropathy

Bw35

   

[46]

Netherland

 Idiopathic IgA nephropathy

B35

DR5

B7,B8

DR2,DR3

[36]

China

 IgA nephropathy

 

DR14, DR3

 

DR7

[47]

Sweden

 IgA nephropathy

 

DR4

  

[16]

France

 IgA nephropathy

 

DQB1*0301

  

[48]

Japan

 IgA nephropathy

Bw35

DR4

  

[41]

Japan

 IgA nephropathy

 

DQw4

  

[49]

France

 Membranous GN

 

DR3

  

[50]

Taiwan

 Membranous GN

 

DR3

  

[51]

UnitedStates

 Membranous GN

 

DR3, DR5

 

DR7

[52]

Netherland

 Idiopathic MN

B8

DR3

  

[53]

South Africa

 HBV- associated membranous GN in children

 

DQB1*0603

  

[54]

Korea

 HBV associated GN

 

DR2, DRB1*15:01, DRB1*15:02

 

DRB1*1302, DQB1*0402, DQB1*0604

[27]

United States

 Heroin- associated nephropathy

Bw53

   

[55]

United States

 Hypertensive renal failure

B35

DR3

A1, B8

 

[56]

Brazil

 Idiopathic FSGS

 

DR4

  

[25]

 

Systemic diseases

     

Mexico

 Type 2 diabetes mellitus with ESRD

 

DRB1*1502 DQB1*0501

 

DRB1*0407

[34]

London

 Early diabetic nephropathy

A2

   

[24]

Turkey

 Amyloidosis and diabetic nephropathy

B58

DR*03

  

[30]

United States

 Diabetic nephropathy

   

DRB1*04

[29]

Canada

 Diabetes related ESRD in ≤ 50y

A2

DR4, DR8

  

[15]

Egypt

 Diabetic nephropathy

A2, B8

DRB1*3, DRB1*11

  

[35]

  1. DESRD diabetic related end stage renal disease
  2. y years
  3. *Results of this study