Fig. 2From: Putative novel mediators of acute kidney injury in critically ill patients: handling by continuous venovenous hemofiltration and effect of anticoagulation modalitiesConcentration of angiopoietin-2 during CVVH over time at inlet (before addition of replacement fluid), outlet, ultrafiltrate, and total mass removal rate and sieving coefficient (median and interquartile range). Symbols: ● no anticoagulation, ■ heparin, ▲ citrate. The concentration at inlet minimally decreased over time, irrespective of anticoagulation (P = 0.001). The concentration in ultrafiltrate decreased over time in the no anticoagulation group, but not in the other groups (P < 0.001). The sieving coefficient decreased in the no anticoagulation group, but not in the others groups (P < 0.001 for interaction anticoagulation and time)Back to article page