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Table 5 Validation group: Correlations, bias, precision and accuracy of the different GFR prediction methods and measured 24hU-CrCl
| Correlation coefficient R | SEE† | BIAS Median difference† | ABSOLUTE BIAS† | PRECISION IQR (P25, P75) of differences† | ACCURACY | |||
|---|---|---|---|---|---|---|---|---|
| P15 (%) | P30 (%) | |||||||
| All subjects (N = 31) | mCrCl | 0.972*** | 8.8 | 0 | 4.4 | 7.9 (-4.3, 3.6) | 27 (87)a | 30 (97)bcd |
| 4vMDRD | 0.935*** | 11.4 | −8.3 | 8.9 | 13.7 (-18.8, -5.2) | 8 (26) | 25 (81) | |
| CKD-EPI | 0.932*** | 13.0 | −7.0 | 7.2 | 12.1 (-15.7, -3.6) | 9 (29) | 26 (84) | |
| CG-CrCl | 0.920*** | 14.2 | −4.4 | 7.1 | 9.0 (-8.7, 0.4) | 17 (55) | 28 (90) | |
| Male (N = 15) | mCrCl | 0.958*** | 11.3 | 0.8 | 7.3 | 15.5 (-11.5, 4.0) | 13 (87) | 15 (100) |
| 4vMDRD | 0.961*** | 9.0 | −17.0 | 17.0 | 21.9 (-28.7, -6.8) | 3 (20) | 12 (80) | |
| CKD-EPI | 0.967*** | 9.2 | −8.4 | 8.4 | 17.1 (- 23.3, -6.2) | 4 (27) | 14 (93) | |
| CG-CrCl | 0.965*** | 9.6 | −8.8 | 8.8 | 11.2 (-15.5, -4.3) | 8 (53) | 14 (93) | |
| Female (N = 16) | mCrCl | 0.967*** | 5.9 | −0.6 | 4.2 | 7.3 (-4.2, 3.1) | 15 (94) | 15 (94) |
| 4vMDRD | 0.915*** | 10.8 | −5.9 | 7.4 | 6.3 (-10.2, -3.9) | 5 (31) | 11 (69) | |
| CKD-EPI | 0.916*** | 12.4 | −4.8 | 5.9 | 6.7 (-8.7, -1.9) | 5 (31) | 11 (69) | |
| CG-CrCl | 0.893*** | 14.4 | −1.1 | 4.0 | 7.6 (-5.6, 1.9) | 8 (50) | 13 (81) | |
| CrCl > 60 (N = 11) | mCrCl | 0.677* | 10.3 | 0.7 | 11 | 17.8 (-11.5, 6.3) | 10 (91) | 11 (100) |
| 4vMDRD | 0.214º | 15.5 | −22.0 | 24.4 | 22.1 (-34.5, -12.4) | 2 (18) | 8 (73) | |
| CKD-EPI | 0.153º | 16.8 | −18.4 | 19.0 | 23.6 (-25.5, -1.9) | 4 (36) | 10 (91) | |
| CG-CrCl | 0.247º | 20.3 | −8.1 | 9.4 | 13.0 (-17.8, -4.8) | 4 (36) | 10 (91) | |
| CrCl 30 to 60 (N = 11) | mCrCl | 0.756** | 7.0 | −3.8 | 5.9 | 7.8 (-5.2, 2.7) | 10 (91) | 11 (100) |
| 4vMDRD | 0.744** | 4.7 | −8.0 | 8.0 | 5.4 (-10.8, -5.4) | 4 (36) | 9 (82) | |
| CKD-EPI | 0.731* | 5.0 | −7.0 | 7.0 | 5.1 (-10.8, -5.7) | 3 (27) | 9 (82) | |
| CG-CrCl | 0.695* | 7.1 | −3.3 | 5.1 | 6.8 (-7.5, -0.6) | 6 (55) | 11 (100) | |
| CrCl < 30 (N = 9) | mCrCl | 0.767** | 3.9 | 1.4 | 1.5 | 2.3 (-0.2, 2.1) | 8 (89) | 8 (89) |
| 4vMDRD | 0.672* | 2.8 | −6.2 | 6.2 | 3.0 (-7.2, -4.2) | 2 (22) | 7 (78) | |
| CKD-EPI | 0.593º | 3.4 | −6.4 | 6.4 | 4.0 (-8.2, -4.2) | 2 (22) | 7 (78) | |
| CG-CrCl | 0.300º | 7.4 | −0.6 | 4.2 | 6.0 (-4.2, 1.9) | 4 (44) | 7 (78) | |
| BMI > 30 (N = 8) | mCrCl | 0.989*** | 6.8 | 0.1 | 2.7 | 7.3 (-5.9, 1.4) | 7 (88) | 8 (100) |
| 4vMDRD | 0.876** | 21.2 | −10.3 | 16.3 | 19.7 (-25.5, -5.9) | 0 | 3 (38) | |
| CKD-EPI | 0.861** | 24.6 | −8.8 | 14.1 | 16.2 (-22.0, -5.9) | 0 | 6 (75) | |
| CG-CrCl | 0.874** | 25.5 | −6.1 | 7.1 | 9.5 (-7.7, 1.8) | 4 (93) | 7 (88) | |
| BMI > 25 bis 29.9 (N = 16) | mCrCl | 0.956*** | 10.8 | −0.4 | 4.3 | 8.1 (-4.3, 3.8) | 14 (88) | 15 (94) |
| 4vMDRD | 0.963*** | 7.7 | −6.8 | 6.8 | 10.3 (-14.2, -3.9) | 7 (44) | 13 (81) | |
| CKD-EPI | 0.972*** | 7.5 | −6.7 | 6.7 | 9.0 (-12.0, -3.0) | 5 (31) | 13 (81) | |
| CG-CrCl | 0.963*** | 8.0 | −3.1 | 7.8 | 10.7 (-10.0, 0.7) | 9 (56) | 14 (88) | |
| BMI < 24.9 (N = 7) | mCrCl | 0.984*** | 6.5 | 0.8 | 5.9 | (-11, 0.8)†† | 7 (100) | 7 (100) |
| 4vMDRD | 0.983*** | 5.6 | −11.0 | 11.0 | (-33.0, -5.3)†† | 1 (14) | 6 (86) | |
| CKD-EPI | 0.971*** | 8.7 | −6.0 | 6.0 | (-26.0, -0.8)†† | 3 (43) | 7 (100) | |
| CG-CrCl | 0.950*** | 10.7 | −4.2 | 4.2 | (-32.7, 1.8)†† | 4 (57) | 7 (100) | |
