| |
Correlation coefficient R
|
SEE†
|
BIAS Median difference†
|
ABSOLUTE BIAS†
|
PRECISION IQR (P25, P75) of differences†
|
ACCURACY
|
---|
P15 (%)
|
P30 (%)
|
---|
All subjects (N = 31)
|
mCrCl
|
0.972***
|
8.8
|
0
|
4.4
|
7.9 (-4.3, 3.6)
|
27 (87)a
|
30 (97)bcd
|
4vMDRD
|
0.935***
|
11.4
|
−8.3
|
8.9
|
13.7 (-18.8, -5.2)
|
8 (26)
|
25 (81)
|
CKD-EPI
|
0.932***
|
13.0
|
−7.0
|
7.2
|
12.1 (-15.7, -3.6)
|
9 (29)
|
26 (84)
|
CG-CrCl
|
0.920***
|
14.2
|
−4.4
|
7.1
|
9.0 (-8.7, 0.4)
|
17 (55)
|
28 (90)
|
Male (N = 15)
|
mCrCl
|
0.958***
|
11.3
|
0.8
|
7.3
|
15.5 (-11.5, 4.0)
|
13 (87)
|
15 (100)
|
4vMDRD
|
0.961***
|
9.0
|
−17.0
|
17.0
|
21.9 (-28.7, -6.8)
|
3 (20)
|
12 (80)
|
CKD-EPI
|
0.967***
|
9.2
|
−8.4
|
8.4
|
17.1 (- 23.3, -6.2)
|
4 (27)
|
14 (93)
|
CG-CrCl
|
0.965***
|
9.6
|
−8.8
|
8.8
|
11.2 (-15.5, -4.3)
|
8 (53)
|
14 (93)
|
Female (N = 16)
|
mCrCl
|
0.967***
|
5.9
|
−0.6
|
4.2
|
7.3 (-4.2, 3.1)
|
15 (94)
|
15 (94)
|
4vMDRD
|
0.915***
|
10.8
|
−5.9
|
7.4
|
6.3 (-10.2, -3.9)
|
5 (31)
|
11 (69)
|
CKD-EPI
|
0.916***
|
12.4
|
−4.8
|
5.9
|
6.7 (-8.7, -1.9)
|
5 (31)
|
11 (69)
|
CG-CrCl
|
0.893***
|
14.4
|
−1.1
|
4.0
|
7.6 (-5.6, 1.9)
|
8 (50)
|
13 (81)
|
CrCl > 60 (N = 11)
|
mCrCl
|
0.677*
|
10.3
|
0.7
|
11
|
17.8 (-11.5, 6.3)
|
10 (91)
|
11 (100)
|
4vMDRD
|
0.214º
|
15.5
|
−22.0
|
24.4
|
22.1 (-34.5, -12.4)
|
2 (18)
|
8 (73)
|
CKD-EPI
|
0.153º
|
16.8
|
−18.4
|
19.0
|
23.6 (-25.5, -1.9)
|
4 (36)
|
10 (91)
|
CG-CrCl
|
0.247º
|
20.3
|
−8.1
|
9.4
|
13.0 (-17.8, -4.8)
|
4 (36)
|
10 (91)
|
CrCl 30 to 60 (N = 11)
|
mCrCl
|
0.756**
|
7.0
|
−3.8
|
5.9
|
7.8 (-5.2, 2.7)
|
10 (91)
|
11 (100)
|
4vMDRD
|
0.744**
|
4.7
|
−8.0
|
8.0
|
5.4 (-10.8, -5.4)
|
4 (36)
|
9 (82)
|
CKD-EPI
|
0.731*
|
5.0
|
−7.0
|
7.0
|
5.1 (-10.8, -5.7)
|
3 (27)
|
9 (82)
|
CG-CrCl
|
0.695*
|
7.1
|
−3.3
|
5.1
|
6.8 (-7.5, -0.6)
|
6 (55)
|
11 (100)
|
CrCl < 30 (N = 9)
|
mCrCl
|
0.767**
|
3.9
|
1.4
|
1.5
|
2.3 (-0.2, 2.1)
|
8 (89)
|
8 (89)
|
4vMDRD
|
0.672*
|
2.8
|
−6.2
|
6.2
|
3.0 (-7.2, -4.2)
|
2 (22)
|
7 (78)
|
CKD-EPI
|
0.593º
|
3.4
|
−6.4
|
6.4
|
4.0 (-8.2, -4.2)
|
2 (22)
|
7 (78)
|
CG-CrCl
|
0.300º
|
7.4
|
−0.6
|
4.2
|
6.0 (-4.2, 1.9)
|
4 (44)
|
7 (78)
|
BMI > 30 (N = 8)
|
mCrCl
|
0.989***
|
6.8
|
0.1
|
2.7
|
7.3 (-5.9, 1.4)
|
7 (88)
|
8 (100)
|
4vMDRD
|
0.876**
|
21.2
|
−10.3
|
16.3
|
19.7 (-25.5, -5.9)
|
0
|
3 (38)
|
CKD-EPI
|
0.861**
|
24.6
|
−8.8
|
14.1
|
16.2 (-22.0, -5.9)
|
0
|
6 (75)
|
CG-CrCl
|
0.874**
|
25.5
|
−6.1
|
7.1
|
9.5 (-7.7, 1.8)
|
4 (93)
|
7 (88)
|
BMI > 25 bis 29.9 (N = 16)
|
mCrCl
|
0.956***
|
10.8
|
−0.4
|
4.3
|
8.1 (-4.3, 3.8)
|
14 (88)
|
15 (94)
|
4vMDRD
|
0.963***
|
7.7
|
−6.8
|
6.8
|
10.3 (-14.2, -3.9)
|
7 (44)
|
13 (81)
|
CKD-EPI
|
0.972***
|
7.5
|
−6.7
|
6.7
|
9.0 (-12.0, -3.0)
|
5 (31)
|
13 (81)
|
CG-CrCl
|
0.963***
|
8.0
|
−3.1
|
7.8
|
10.7 (-10.0, 0.7)
|
9 (56)
|
14 (88)
|
BMI < 24.9 (N = 7)
|
mCrCl
|
0.984***
|
6.5
|
0.8
|
5.9
|
(-11, 0.8)††
|
7 (100)
|
7 (100)
|
4vMDRD
|
0.983***
|
5.6
|
−11.0
|
11.0
|
(-33.0, -5.3)††
|
1 (14)
|
6 (86)
|
CKD-EPI
|
0.971***
|
8.7
|
−6.0
|
6.0
|
(-26.0, -0.8)††
|
3 (43)
|
7 (100)
|
CG-CrCl
|
0.950***
|
10.7
|
−4.2
|
4.2
|
(-32.7, 1.8)††
|
4 (57)
|
7 (100)
|
- ***p < 0.001; **p < 0.01; *p < 0.05; ºnon significant
- †displayed in mL/min/1.73 m2; ††(Minimum, Maximum)
- ap < 0.005 vs the three other methods; bp = 0.07 vs 4vMDRD; cp = 0.21 vs CKD-EPI;dp = 0.50 vs CG