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Table 5 Quality of the risk factors for falling upon comparing fallers to non-fallers according the GRADE approach (based on our systematic review). Variables evaluated in different studies were heterogeneous, therefore only age, frailty, previous falls and polypharmacy could be analyzed

From: Renal disease and accidental falls: a review of published evidence

Outcome

No. of studies

Design

No quality

Inconsistency

Indirectness

No effect size

Quality

Age

4 studies (700 subjects)

Prospective cohort studies

Very serious

Serious

Serious

Very serious

Very low

Frailty

2 studies define this specifically, four others are related (857 subjects)

Prospective cohort and cross sectional studies

No

Little or no

No

No

Low

Previous falls

3 studies (405 subjects)

Prospective cohort studies

Little or no

No

Little or no

No

Low

Polypharmacy

3 studies (3598 total subjects; 1905 in case and control study)

Prospective cohort and retrospective case–control studies

Serious

Serious

Very serious

Serious

Very low