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Table 1 Patient clinical characteristics, medication use and laboratory parameters, overall and by the presence of abdominal calcification

From: Comparison of single CT scan assessment of bone mineral density, vascular calcification and fat mass with standard clinical measurements in renal transplant subjects: the ABC HeART study

 

Total

ACI Score = 0

ACI Score >0

p-value

(n = 64)

(n = 22)

(n = 42)

Demographics & Clinical features

Age (years), mean (sd)

47.3 (13.0)

35.8 (8.5)

52.3 (9.6)

0.001

Male: n (%)

39 (61 %)

18 (75 %)

21 (52 %)

0.07

Dialysis Modality:

   

0.95

Haemodialysis

39 (60.9 %)

15 (62.5 %)

24 (60 %)

Peritoneal dialysis

23 (35.9 %)

8 (33.3 %)

15 (37.5 %)

None (Pre-emptive)

2 (3.2 %)

1 (4.2 %)

1 (2.5 %)

Duration of dialysis (years),

2.3

1.6

3.0

0.03

Median (IQR)

(1.6, 3.3)

(0.8, 2.0)

(1.7, 3.8)

Duration of Transplant (years),

3.7

3.2

4.1

0.40

Median (IQR)

(0.9, 8.1)

(0.9, 8.8)

(0.9, 7.1)

Mean Arterial BP (mm Hg), Mean (sd)

102.7 (9.7)

100.0 (8.8)

104.7 (8.9)

0.01

Body Mass Index (Kg/m2)

25.6

23.7

26.0

0.16

Median (IQR)

(22.8, 30.0)

(22.1, 29.3)

(23.4, 30.1)

Diabetes: N (%)

10 (15.6 %)

3 (12.5 %)

7 (17.5 %)

0.60

Ever Smoked: N (%)

28 (43.8 %)

8 (33.3 %)

20 (50 %)

0.19

Prior parathyroidectomy N (%)

8 (12.5 %)

3 (12.5 %)

5 (12.5 %)

1.0

Past History CV event: N (%)

6

0

6

0.05

Current Medication Use

Tacrolimus: N (%)

56 (87.5 %)

21 (87.5 %)

35 (87.5 %)

1.0

Mycophenolate mofetil: N (%)

52 (81.2 %)

17 (70.8 %)

35 (87.5 %)

0.10

Corticosteroid, N (%)

28 (43.8 %)

10 (41.7 %)

18 (45 %)

0.80

Vitamin D: N (%)

5

1

4

0.64

Laboratory parameters

eGFR (ml/min per1.73 m2) mean (sd)

54.1 (17.6)

57.8 (14.8)

48.3 (14.9)

0.002

iPTH (ng/ml), median (IQR)

91.5 (73,108)

106.5 (83.5, 75.0)

86.5 (57,128)

0.85

Alkaline Phosphatase

106.2 (50.7)

106.5 (38.3)

106.0 (57.3)

0.97

Serum calcium (mmol/L), mean (sd)

2.57 (0.17)

2.52 (0.16)

2.63 (0.17)

0.06

Serum Phosphate (mmol/L), mean (sd)

1.01 (0.22)

1.00 (0.24)

1.02 (0.21)

0.70

Serum Cholesterol (mmol/L), Mean (sd)

4.7 (1.1)

4.2 (0.9)

5.0 (1.0)

0.006

Serum LDL Cholesterol (mmol/L), mean (sd)

2.65 (0.91)

2.34 (0.78)

2.82 (0.94)

0.06

Serum HDL Cholesterol (mmol/L), mean (sd)

1.35 (0.40)

1.28 (0.35)

1.39 (0.42)

0.36