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Table 1 NEPTUNE Urine Collection Timeline

From: Strategy and rationale for urine collection protocols employed in the NEPTUNE study

Visit Numbera

V1

V2

V3

V4

V5

V6

V7

V8

V9

V10

V11

V12

V13

Eligibility assessment

X

            

Baseline H&P

 

X

           

Follow-up H&P

   

X

X

X

X

X

X

X

X

X

X

Biosample baseline

 

X

           

Biosample follow-up

   

X

X

X

X

X

X

X

X

X

X

24-hour urine

 

X

 

X

X

X

 

X

 

X

 

X

X

Clean catch/(Spot) urine

 

X

 

X

X

X

X

X

X

X

X

X

X

Renal biopsy tissue

  

Xb

          
  1. Abbreviations: H&P history and physical examination, UA urinalysis, macroscopic (color, appearance, specific gravity, pH, leukocyte esterase, nitrite, protein, glucose, ketones, urobilin, bilirubin, blood), V visit
  2. aThere will be a total of 13 visits for the anticipated 600 participants in the study. In each visit, a total of 11 tubes will be generated (3 of 5 mL tubes, 7 of 2 mL tubes and 1 of 50 mL tube)
  3. bRenal biopsy includes a pre-biopsy 10 mL spot urine