Parameter | All (n=199) | mGFR <60 (n=60) | mGFR 60-90 (n=63) | mGFR >90 (n=76) | p value |
---|---|---|---|---|---|
Age (Yr) | 62.8 ± 12.7 | 70.9 ± 10.8 | 65.4 ± 9.2 | 54.3 ± 11.3 | <0.001 |
Gender (% males) | 67 | 65 | 65 | 70 | 0.79 |
Type diabetes (% T1/T2) | 25/75 | 15/85 | 21/79 | 37/63 | 0.009 |
Duration of diabetes (Years) | 18.0 ± 11.4 | 20.9 ± 12.0 | 19.1 ± 12.7 | 14.8 ± 8.9 | 0.007 |
Height (cm) | 168.6 ± 9.3 | 167.5 ± 9.2 | 167.5 ± 9.6 | 170.5 ± 8.9 | 0.12 |
Weight (kg) | 88.8 ± 21.1 | 85.8 ± 19.6 | 89.3 ± 24.5 | 90.7 ± 19.3 | 0.41 |
BMI (kg/m2) | 31.1 ± 7.0 | 30.2 ± 6.0 | 31.8 ± 8.5 | 31.1 ± 6.1 | 0.46 |
mGFR (ml/min/1.73m2) | 80.0 ± 30.9 | 44.2 ± 10.8 | 75.5 ± 9.8 | 111.8 ± 17.0 | <0.001 |
MDRD (ml/min/1.73m2) | 78.4 ± 28.2 | 48.2 ± 13.3 | 79.5 ± 17.5 | 100.8 ± 22.5 | <0.001 |
CKD-EPI (ml/min/1.73m2) | 78.4 ± 24.9 | 49.5 ± 14.2 | 80.7 ± 15.2 | 99.4 ± 13.1 | <0.001 |
AER (μg/min) | 10.4 (4.3, 26.3) | 20.7 (7.6, 71.3) | 5.8 (3.5, 19.1) | 8.6 (4.3, 20.7) | 0.47 |
AER (% normo/micro/macro) | 69.2/24.7/6.1 | 54.2/32.2/13.6 | 69.8/23.8/6.4 | 80.3/19.7/0 | 0.004 |
HbA1C (%) | 7.60 ± 1.1 | 7.35 ± 1.0 | 7.42 ± 0.085 | 7.94 ± 1.3 | 0.002 |
HbA1C (mmol/mole) | 60 | 57 | 58 | 63 | 0.002 |
Systolic blood pressure (mmHg) | 131.9 ± 14.6 | 135.2 ± 17.4 | 132.7 ± 15.2 | 128.7 ± 10.8 | 0.03 |
Diastolic blood pressure (mmHg) | 71.4 ± 10.1 | 67.9 ± 9.6 | 72.2 ± 10.9 | 73.5 ± 9.2 | 0.005 |
Any blood pressure therapy (%) | 81 | 88 | 82 | 76 | 0.21 |
ACE inhibitor therapy (%) | 47 | 52 | 42 | 46 | 0.65 |
Lipid lowering therapy (%) | 83 | 88 | 89 | 76 | 0.08 |
Fenofibrate therapy (%) | 8 | 11 | 8 | 5 | 0.55 |
Retinopathy () | 53 | 61 | 51 | 48 | 0.34 |
IHD (%) | 31 | 39 | 38 | 19 | 0.02 |
CVD (%) | 5 | 5 | 7 | 3 | 0.56 |
PVD (%) | 13 | 25 | 12 | 4 | 0.002 |
History of macrovascular disease (%) | 40 | 49 | 48 | 23 | 0.002 |