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Table 3 Summary of bias, precision and accuracy of the MDRD and CKD-EPI equations compared to mGFR-CKD stage 1: ≥ 90, stage 2: 60-89 and < stage 3: < 60 ml/min/1.73 m2. Bias = eGFR-mGFR, precision = SD of the bias and accuracy = the proportion of results falling within 15 % or 30 % of mGFR values

From: The Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation does not improve the underestimation of Glomerular Filtration Rate (GFR) in people with diabetes and preserved renal function

MDRD

Bias

P(15)

P(30)

GFR >90 ml/min/1.73m2 (n=76)

-11.0 ± 18.3

47.4 %

89.5 %

GFR 60-90 ml/min/1.73m2 (n=63)

+3.8 ± 14.3

58.7 %

79.4 %

GFR <60 ml/min/1.73m2 (n=60)

+4.6 ± 1.0

43.3 %

83.3 %

p value

<0.001

0.06

0.57

CKD-EPI

Bias

P(15)

P(30)

GFR <90 ml/min/1.73m2 (n=76)

-12.4 ± 12.2

69.7 %

97.4 %

GFR <60-90 ml/min/1.73m2 (n=63)

+5.0 ± 11.9

57.1 %

87.3 %

GFR <60 ml/min/1.73m2 (n=60)

+5.3 ± 10.8

40.0 %

78.3 %

p value

<0.001

0.002

0.001

  1. * P < 0.05 vs MDRD
  2. mGFR measured Glomerular Filtration Rate, CKD chronic kidney disease, MDRD modification of diet in renal disease, CKD-EPI Chronic Kidney Disease-Epidemiology Collaboration, P(15) proportion of results falling within 15 % of mGFR values, P(30) proportion of results falling within 30 % of mGFR values