Skip to main content

Table 3 Shows characteristics of allografts with post-transplant MPGN recurrence

From: Membranoproliferative glomerulonephritis recurrence after kidney transplantation: using the new classification

Graft

MPGN type (Native/Rec)

Age at Txp

Sex/Race

Donor

Months to recurrence

sCr

Proteinuria(g)

Rx

Graft status/sCr

By EM

By IF

1

1/1

IC/IC

20

F/AA

LR

2

1.4

4

None

Functional/1.6

2

1 a/1

IC/IC

39

F/C

LR

3

1.2

9

CS + ACEi

Functional/ 2.5

3

1 a/1

C3/IC

59

F/C

LR

1

0.9

2.7

None

Functional/0.9

4

1/1

IC/IC

26

M/C

LR

24

2

2.3

Ritux + CS

Lost in 22 mos

5

2 + 3/2 + 3

IC/IC

53

M/C

D

24

3

NA

CS

Lost in 96 mos

6

3 a/1

IC/IC

18

M/I

LU

36

2.5

4

TPE + CS

Lost in 4 mos

7

3 a/?

IC/IC

15

M/I

LR

18

NA

NA

None

Lost in 1 mos

8

1/1

IC/IC

28

M/A

LR

6

1.8

0.1

Ritux

Functional/1.2

9

1/1

IC/IC

54

M/AA

D

4

1.0

2

ACEi

Functional/1.0

10

1/1

IC/IC

53

M/C

D

4

1.7

0.5

TPE+ ACEi

Functional/1.2

11

3a/1

IC/IC

30

F/C

LR

108

2.0

0.45

Ritux

Functional/2.5

12

2/2

IC/IC

54

M/C

LU

24

3.4

NA

Ritux

Lost in 2 mos

13

1/1

IC/IC

51

F/C

LU

1

1.9

0.8

TPE + Ritux

Functional/1.7b

14

1a/1

IC/IC

32

M/H

LR

24

1.7

4

TPE + Ritux

Lost in 41 mos

15

1/1

IC/IC

25

F/C

LR

14

1.3

9.5

Ritux

Lost in 4 mos

16

1/1

IC/IC

53

F/AA

LR

12

NA

NA

CS

Lost in 8 mos

17

1/2

IC/C3

58

F/AA

D

6

3.1

NA

None

Lost in 5 mos

18

1/1

C3/C3

24

M/C

LU

3

1.3

0.2

Eculizumab

Functional/1.3

  1. Txp transplant, IC immune complex, sCr serum Creatinine, Rx Treatment, AA African American, C Caucasian, I Indian, A Asian, H Hispanic, LR living related, LU living unrelated, D: deceased, CS corticosteroids, ACEi Angiotensin Converting Enzyme inhibitor, TPE therapeutic plasma exchange, Ritux Rituximab, NA not available
  2. aMPGN type by documentation but kidney biopsy slides are not available for review. All others are classified based on kidney biopsy slides review
  3. bPatient diagnosed with plasma cell dyscrasia and received chemotherapy