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Table 2 Association of anemia with baseline cognitive impairment among participants age ≥55 in the Chronic Renal Insufficiency Cohort

From: Anemia and risk for cognitive decline in chronic kidney disease

Cognitive test

N

Odds ratio (95 % CI)

Model 1

Model 2

Model 3

Modified Mini-Mental State Exam

762

1.48 (0.85–2.59)

1.45 (0.81–2.61)

1.59 (0.86–2.94)

Category Fluency

760

1.49 (0.92–2.41)

1.50 (0.91–2.48)

1.43 (0.85–2.40)

Buschke Delayed Recall

753

1.19 (0.77–1.86)

1.19 (0.75–1.89)

1.06 (0.66–1.71)

Boston Naming

760

1.34 (0.83–2.16)

1.21 (0.73–2.00)

1.25 (0.73–2.14)

Trailmaking Test A

759

1.93 (1.12–3.32)

1.72 (0.98–3.04)

1.72 (0.95–3.10)

Trailmaking Test B

759

1.42 (0.89–2.28)

1.19 (0.73–1.96)

1.16 (0.69–1.94)

  1. Model 1 is adjusted for age, sex, race, education and CRIC clinical center
  2. Model 2 is adjusted for age, sex, race, education, diabetes, hypertension, coronary artery disease, peripheral vascular disease, stroke, alcohol use, and CRIC clinical center
  3. Model 3 is adjusted for age, sex, race, education, CRIC clinical center, diabetes, hypertension, coronary artery disease, peripheral vascular disease, stroke, alcohol use, and estimated glomerular filtration rate