From: KNOW-Ped CKD (KoreaN cohort study for outcomes in patients with pediatric CKD): Design and methods
CKD Stage | Total | I | II | IIIa | IIIb | IV | V |
---|---|---|---|---|---|---|---|
Patient Number | 322 | 50 (15.5) | 61 (18.9) | 54 (16.8) | 56 (17.4) | 60 (18.6) | 41 (12.7) |
M:F (Male, %) | 218:104 (67.7) | 31:19 (62.0) | 43:18 (70.5) | 33:21 (61.1) | 36:20 (64.3) | 42:18 (70.0) | 33:8 (80.5) |
Age (years) | 10.00 ± 5.45 | 7.04 ± 4.22 | 10.39 ± 5.61 | 11.50 ± 5.08 | 9.95 ± 5.36 | 9.48 ± 5.71 | 11.90 ± 5.42 |
Primary Kidney Disease | |||||||
 CAKUT | 198 (61.49) | 17 (34.00) | 38 (62.3) | 30 (55.56) | 41 (73.21) | 43 (71.67) | 29 (70.73) |
 GN | 93 (28.88) | 31 (62.00) | 16 (26.23) | 15 (27.78) | 12 (21.43) | 10 (16.67) | 9 (21.95) |
 Others | 31 (9.63) | 2 (4.00) | 7 (11.48) | 9 (16.67) | 3 (5.36) | 7 (11.67) | 3 (7.32) |
Age Group | |||||||
 <2 years | 31 (9.63) | 6 (12.00) | 6 (9.83) | 2 (3.70) | 4 (7.14) | 9 (15.00) | 4 (9.76) |
 2–5 years | 50 (15.53) | 13 (26.00) | 12 (19.67) | 8 (14.81) | 8 (14.29) | 7 (11.67) | 2 (4.88) |
 6–11 year | 91 (28.26) | 21 (42.00) | 8 (13.11) | 12 (22.22) | 20 (35.71) | 20 (33.33) | 10 (24.39) |
 12–19 years | 150 (46.58) | 10 (20.00) | 35 (57.373) | 32 (59.26) | 24 (42.856) | 24 (40.00) | 25 (60.98) |
Growth, z score | |||||||
 Height | −0.88 ± 1.43 | −0.42 ± 1.09 | −0.49 ± 1.41 | −0.61 ± 1.32 | −1.11 ± 1.22 | −1.33 ± 1.62 | −1.43 ± 1.58 |
 Weight | −0.91 ± 1.65 | −0.24 ± 1.39 | −0.56 ± 1.69 | −0.67 ± 1.34 | −1.01 ± 1.4 | −1.68 ± 1.88 | −1.34 ± 1.7 |
eGFR (mL/min/1.73 m2) | 53.1 ± 40.22 | 127.39 ± 36.16 | 68.98 ± 10.21 | 52.28 ± 4.57 | 36.03 ± 4.7 | 20.87 ± 5.42 | 10.46 ± 3.02 |
Hemoglobin (g/dL) | 12.1 ± 1.95 | 12.49 ± 1.21 | 13 ± 2.1 | 12.61 ± 1.94 | 12.34 ± 1.89 | 11.19 ± 1.6 | 10.65 ± 1.74 |
Transferrin saturation (%) | 27 ± 16 | 29 ± 28 | 26 ± 13 | 27 ± 13 | 28 ± 13 | 25 ± 12 | 29 ± 12 |
Cholesterol (mg/dL) | 183 ± 59 | 197 ± 86 | 175 ± 46 | 190 ± 50 | 179 ± 574 | 184 ± 504 | 171 ± 61 |
Intact PTH (pg/mL) | 119 ± 178 | 40 ± 39 | 46 ± 22 | 66 ± 47 | 99 ± 857 | 193 ± 217 | 302 ± 327 |
25(OH)D3 (ng/mL) | 20.86 ± 10.09 | 20.02 ± 8.75 | 20 ± 10.62 | 21 ± 9 | 22 ± 9 | 21 ± 11 | 19 ± 10 |
u Protein/Cr (mg/mg) | 1.77 ± 5.95 | 3.76 ± 14.36 | 0.8 ± 2.09 | 1.17 ± 2.08 | 1.44 ± 2.29 | 1.9 ± 2.01 | 1.88 ± 1.52 |
LVMI (g/m2.7) | 70 ± 22 | 71 ± 21 | 71 ± 23 | 65 ± 18 | 66 ± 17 | 70 ± 24 | 80 ± 26 |