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Table 4 Clinical characteristics of KNOW-Ped CKD

From: KNOW-Ped CKD (KoreaN cohort study for outcomes in patients with pediatric CKD): Design and methods

CKD Stage Total I II IIIa IIIb IV V
Patient Number 322 50 (15.5) 61 (18.9) 54 (16.8) 56 (17.4) 60 (18.6) 41 (12.7)
M:F (Male, %) 218:104 (67.7) 31:19 (62.0) 43:18 (70.5) 33:21 (61.1) 36:20 (64.3) 42:18 (70.0) 33:8 (80.5)
Age (years) 10.00 ± 5.45 7.04 ± 4.22 10.39 ± 5.61 11.50 ± 5.08 9.95 ± 5.36 9.48 ± 5.71 11.90 ± 5.42
Primary Kidney Disease
 CAKUT 198 (61.49) 17 (34.00) 38 (62.3) 30 (55.56) 41 (73.21) 43 (71.67) 29 (70.73)
 GN 93 (28.88) 31 (62.00) 16 (26.23) 15 (27.78) 12 (21.43) 10 (16.67) 9 (21.95)
 Others 31 (9.63) 2 (4.00) 7 (11.48) 9 (16.67) 3 (5.36) 7 (11.67) 3 (7.32)
Age Group
 <2 years 31 (9.63) 6 (12.00) 6 (9.83) 2 (3.70) 4 (7.14) 9 (15.00) 4 (9.76)
 2–5 years 50 (15.53) 13 (26.00) 12 (19.67) 8 (14.81) 8 (14.29) 7 (11.67) 2 (4.88)
 6–11 year 91 (28.26) 21 (42.00) 8 (13.11) 12 (22.22) 20 (35.71) 20 (33.33) 10 (24.39)
 12–19 years 150 (46.58) 10 (20.00) 35 (57.373) 32 (59.26) 24 (42.856) 24 (40.00) 25 (60.98)
Growth, z score
 Height −0.88 ± 1.43 −0.42 ± 1.09 −0.49 ± 1.41 −0.61 ± 1.32 −1.11 ± 1.22 −1.33 ± 1.62 −1.43 ± 1.58
 Weight −0.91 ± 1.65 −0.24 ± 1.39 −0.56 ± 1.69 −0.67 ± 1.34 −1.01 ± 1.4 −1.68 ± 1.88 −1.34 ± 1.7
eGFR (mL/min/1.73 m2) 53.1 ± 40.22 127.39 ± 36.16 68.98 ± 10.21 52.28 ± 4.57 36.03 ± 4.7 20.87 ± 5.42 10.46 ± 3.02
Hemoglobin (g/dL) 12.1 ± 1.95 12.49 ± 1.21 13 ± 2.1 12.61 ± 1.94 12.34 ± 1.89 11.19 ± 1.6 10.65 ± 1.74
Transferrin saturation (%) 27 ± 16 29 ± 28 26 ± 13 27 ± 13 28 ± 13 25 ± 12 29 ± 12
Cholesterol (mg/dL) 183 ± 59 197 ± 86 175 ± 46 190 ± 50 179 ± 574 184 ± 504 171 ± 61
Intact PTH (pg/mL) 119 ± 178 40 ± 39 46 ± 22 66 ± 47 99 ± 857 193 ± 217 302 ± 327
25(OH)D3 (ng/mL) 20.86 ± 10.09 20.02 ± 8.75 20 ± 10.62 21 ± 9 22 ± 9 21 ± 11 19 ± 10
u Protein/Cr (mg/mg) 1.77 ± 5.95 3.76 ± 14.36 0.8 ± 2.09 1.17 ± 2.08 1.44 ± 2.29 1.9 ± 2.01 1.88 ± 1.52
LVMI (g/m2.7) 70 ± 22 71 ± 21 71 ± 23 65 ± 18 66 ± 17 70 ± 24 80 ± 26