Fig. 7
From: Changes in renal WT-1 expression preceding hypertension development
NADPH activity in mitochondrial fractions from renal cortices during hypertension development. NADPH oxidase activity was observed in SHRs and WKYs: newborn rats (0 W), 2-week-old rats (2 W), 4-week-old rats (4 W), 6-week-old rats (6 W) and 8-week-old rats (8 W). Specifically, NADPH oxidase activity in mitochondrial fractions from kidney cortices increased at week 4 and 6 of hypertension evolution (*p < 0.05, both ages), while it was considerably higher only in the 8-week-old SHR, compared to the normotensive control (WKY) (**p < 0.01). Each bar represents mean ± SEM; n = 5