Skip to main content

Table 1 Body weight, kidney/body weight ratio, and blood pressure in SHRs and WKYs

From: Changes in renal WT-1 expression preceding hypertension development

Strain

0-week-old rat

1-week-old rat

2-week-old rat

3-week-old rat

4-week-old rat

5-week-old rat

6-week-old rat

7-week-old rat

8-week-old rat

SHR

         

Body weight (g)

6 ± 1

13 ± 3

24 ± 4

45 ± 6

82 ± 7

100 ± 10

130 ± 9*

150 ± 9*

160 ± 10*

WKY

         

Body weight (g)

7 ± 1

17 ± 4

29 ± 5

54 ± 7

92 ± 8

115 ± 9

150 ± 8

175 ± 10

190 ± 12

SHR

         

Renal/Body weight (mg/g)

5.60 ± 0.3

6.05 ± 0.90

5.9 ± 1.00

5.86 ± 0.90

6.02 ± 1.10

7 ± 1.30

7.7 ± 1.00

7.5 ± 1.20

8 ± 1.20

WKY

         

Renal/Body weight (mg/g)

6.1 ± 0.30

7.43 ± 1.10

6.66 ± 1.10

6.9 ± 1.20

6.82 ± 1.20

6.3 ± 1.20

7.3 ± 1.10

6.7 ± 1.10

7.3 ± 1.10

SHR

         

SBP (mmHg)

-------

-------

-------

-------

142 ± 11

150 ± 10

195 ± 10**

230 ± 15**

250 ± 20**

WKY

         

SBP (mmHg)

-------

-------

-------

-------

135 ± 8

140 ± 7

145 ± 8

148 ± 7

150 ± 10

  1. Significantly different from the values at 6, 7 and 8 weeks of age in each strain (*p < 0.05 and **p < 0.01). Results are mean ± SEM; n = 5