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Table 3 The size effect of intervention: difference in eGFR decline rate between first and second period of study in treatment group vs control group

From: Efficacy of the Essential Amino Acids and Keto-Analogues on the CKD progression rate in real practice in Russia - city nephrology registry data for outpatient clinic

  eGFR decline rate Standardized effect size
  First 5 visits Second 5 visits Bias corrected (Hedges) Standard error of effect size estimate Confidence interval for effect size
ml/min/1.73 m2 per year
Treatment group −2.71 ± 2.38 −2.01 ± 2.26 0.30 0.15 0.02÷0.58
Control group −2.18 ± 2.01 −2.04 ± 2.18 0.07 0.14 −0.22÷0.35
Difference p = 0.10 p = 0.93 p < 0.001