From: Effect of glycemic index and carbohydrate intake on kidney function in healthy adults
Reducing glycemic index | Change in eGFRcys (95 % CI) | P |
---|---|---|
eGFRcys, mL/min/1.73 m2, unadjusted | 1.90 (1.10, 2.70) | <0.001 |
Adjusted for fasting glucose, insulin, triglycerides | 1.82 (1.01, 2.63) | <0.001 |
Adjusted for uric acid, systolic blood pressure, diastolic blood pressure | 1.47 (0.70, 2.23) | <0.001 |
Adjusted for high sensitivity C-reactive protein | 1.89 (1.09, 2.69) | <0.001 |
Adjusted for all the above | 1.38 (0.62, 2.15) | <0.001 |
Reducing carbohydrate proportion | ||
eGFRcys, mL/min/1.73 m2, unadjusted | 2.97 (1.93, 4.01) | <0.001 |
Adjusted for fasting glucose, insulin, triglycerides | 2.51 (1.45, 3.56) | <0.001 |
Adjusted for uric acid, systolic blood pressure, diastolic blood pressure | 3.27 (2.28, 4.25) | <0.001 |
Adjusted for high sensitivity C-reactive protein | 2.96 (1.92, 4.00) | <0.001 |
Adjusted for all the above | 2.84 (1.83, 3.86) | <0.001 |
Reducing both glycemic index and carbohydrate proportion | ||
eGFRcys, mL/min/1.73 m2, unadjusted | 4.47 (3.49, 5.44) | <0.001 |
Adjusted for fasting glucose, insulin, triglycerides | 3.88 (2.84, 4.92) | <0.001 |
Adjusted for uric acid, systolic blood pressure, diastolic blood pressure | 4.14 (3.22, 5.05) | <0.001 |
Adjusted for high sensitivity C-reactive protein | 4.50 (3.54, 5.46) | <0.001 |
Adjusted for all the above | 3.67 (2.70, 4.64) | <0.001 |