Skip to main content

Table 4 Change in estimated glomerular filtration rate based on cystatin C adjusted for fasting glucose, fasting insulin, fasting triglycerides, uric acid, systolic blood pressure, diastolic blood pressure, and high sensitivity C-reactive protein

From: Effect of glycemic index and carbohydrate intake on kidney function in healthy adults

Reducing glycemic index

Change in eGFRcys (95 % CI)

P

 eGFRcys, mL/min/1.73 m2, unadjusted

1.90 (1.10, 2.70)

<0.001

  Adjusted for fasting glucose, insulin, triglycerides

1.82 (1.01, 2.63)

<0.001

  Adjusted for uric acid, systolic blood pressure, diastolic blood pressure

1.47 (0.70, 2.23)

<0.001

  Adjusted for high sensitivity C-reactive protein

1.89 (1.09, 2.69)

<0.001

  Adjusted for all the above

1.38 (0.62, 2.15)

<0.001

Reducing carbohydrate proportion

 eGFRcys, mL/min/1.73 m2, unadjusted

2.97 (1.93, 4.01)

<0.001

  Adjusted for fasting glucose, insulin, triglycerides

2.51 (1.45, 3.56)

<0.001

  Adjusted for uric acid, systolic blood pressure, diastolic blood pressure

3.27 (2.28, 4.25)

<0.001

  Adjusted for high sensitivity C-reactive protein

2.96 (1.92, 4.00)

<0.001

  Adjusted for all the above

2.84 (1.83, 3.86)

<0.001

Reducing both glycemic index and carbohydrate proportion

 eGFRcys, mL/min/1.73 m2, unadjusted

4.47 (3.49, 5.44)

<0.001

  Adjusted for fasting glucose, insulin, triglycerides

3.88 (2.84, 4.92)

<0.001

  Adjusted for uric acid, systolic blood pressure, diastolic blood pressure

4.14 (3.22, 5.05)

<0.001

  Adjusted for high sensitivity C-reactive protein

4.50 (3.54, 5.46)

<0.001

  Adjusted for all the above

3.67 (2.70, 4.64)

<0.001

  1. Note: eGFRcys represents estimated glomerular filtration rate-based on cystatin C