Skip to main content

Table 2 Association between baseline obesity parameters and the primary outcome in stage 3–4 chronic kidney disease. Comparison performed using Cox proportional hazards modelling to compare body mass index, waist circumference and conicity index with the composite outcome of doubling of serum creatinine, commencement of renal replacement therapy or all-cause mortality

From: Association of anthropometric measures with kidney disease progression and mortality: a retrospective cohort study of pre-dialysis chronic kidney disease patients referred to a specialist renal service

  

HR (95 % CI)

No. (%)

Crude

Model 1

Model 2

Model 3

Body mass index (kg/m2)

 <18.5

15 (1.8)

0.54 (0.17-1.71)

0.43 (0.2-1.99)

0.57 (0.14-2.38)

0.74 (0.17-3.19)

 18.5-24.9

174 (20.7)

1.00 (referent)

1.00 (referent)

1.00 (referent)

1.00 (referent)

 25-29.9

293 (34.8)

0.57 (0.39-0.81)**

0.55 (0.38-0.79)**

0.58 (0.40-0.85)**

0.50 (0.33-0.75)**

 30-39.9

288 (34.2)

0.63 (0.44-0.90)*

0.65 (0.46-0.93)*

0.71 (0.49-1.03)

0.62 (0.41-0.93)*

 ≥40

72 (8.6)

0.74 (0.44-1.24)

0.82 (0.49-1.39)

0.96 (0.56-1.65)

0.94 (0.52-1.69)

Waist circumference tertiles (cm)

 M: <98.5, F < 90

197 (33.2)

1.00 (referent)

1.00 (referent)

1.00 (referent)

1.00 (referent)

 M: 98.5-110, F: 90-101

198 (33.3)

1.23 (0.83-1.82)

1.14 (0.75-1.65)

1.31 (0.86-1.97)

0.99 (0.63-1.56)

 M > 110, F: >101

199 (33.5)

0.87 (0.57-1.33)

0.89 (0.58-1.35)

1.00 (0.64-1.57)

0.87 (0.54-1.41)

Conicity index tertiles

 <1.291

196 (33.3)

1.00 (referent)

1.00 (referent)

1.00 (referent)

1.00 (referent)

 1.291-1.372

196 (33.3)

1.14 (0.74-1.80)

1.03 (0.67-1.59)

1.03 (0.65-1.63)

1.13 (0.68-1.86)

 >1.372

196 (33.3)

1.59 (1.05-2.39)*

1.46 (0.96-2.20)

1.39 (0.88-2.22)

1.16 (0.69 -1.95)

  1. Results expressed as number (percentage) and hazard ratio (95 % confidence interval)
  2. Model 1: Adjusted for age
  3. Model 2: Adjusted for age, gender, race (Caucasian vs. Non-Caucasian)
  4. Model 3: Model 2 + estimated glomerular filtration rate, proteinuria, cause of chronic kidney disease, diabetes status
  5. *P ≤ 0.05, **P ≤ 0.01